A Refined Model for Ionization of Small Molecules in Electrospray Mass Spectrometry

被引：0
作者：
Gao, Fangyuan [1 ,2 ]
Zhang, Lingyi [1 ]
Li, Xiuqin [2 ]
Jiao, Fenglong [3 ]
Zhang, Weibing [1 ]
Zhang, Qinghe [2 ]
机构：
[1] East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China
[2] Natl Inst Metrol, Div Chem Metrol & Analyt Sci, Beijing 100013, Peoples R China
[3] Beijing Inst Technol, Sch Life Sci & Technol, Beijing 100081, Peoples R China
来源：
CHEMISTRY LETTERS | 2016年 / 45卷 / 08期
关键词：
Electrospray; Ionization mechanism; Small molecules; MATRIX; EVAPORATION; EFFICIENCY; PEPTIDES; ANALYTES; IONS;
D O I：
10.1246/cl.160391
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A refined ionization model of small molecules was developed based on a unit of classic models. The ionization process was divided into three sub-processes of diffusion, charge transfer, and ion evaporation. Based on the equations, the impact of a single process and multiprocesses on response was verified by employing special samples, and the relative evaporation energies of several pair of samples were calculated. This model is sensitive to slight differences in ionization energy and allows distinction of the ionization differences during each sub-process.
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页码：955 / 957
页数：3
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