Using Support Vector Machine to Identify Imaging Biomarkers of Major Depressive Disorder and Anxious Depression

被引：0

作者：

Chi, Minyue ^{[2
]}

Guo, Shengwen ^{[2
]}

Ning, Yuping ^{[1
]}

Li, Jie ^{[1
]}

Qi, Haochen ^{[2
]}

Gao, Minjian ^{[3
]}

Wang, Jiexin ^{[3
]}

Hu, Xiaowei ^{[3
]}

Guo, Yangbo ^{[1
]}

Yang, Yuling ^{[1
]}

Peng, Hongjun ^{[1
]}

Wu, Kai ^{[2
]}

机构：

[1] Guangzhou Med Univ, Affiliated Hosp, Guangzhou Psychiat Hosp, Guangzhou, Guangdong, Peoples R China

[2] South China Univ Technol, Sch Mat Sci & Engn, Dept Biomed Engn, Guangzhou 510641, Guangdong, Peoples R China

[3] South China Univ Technol, Sch Comp Sci & Engn, Guangzhou 510641, Guangdong, Peoples R China

来源：

BIO-INSPIRED COMPUTING - THEORIES AND APPLICATIONS, BIC-TA 2014 | 2014年 / 472卷

基金：

中国国家自然科学基金;

关键词：

anxiety; depression; gray matter volume; voxel-based morphometry; support vector machine;

D O I：

暂无

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

Comorbidity with anxiety disorders is a relatively common occurrence in major depressive disorder. However, there are no objective, neurological markers which can be used to identify depressive disorder with and without anxiety disorders. The aim of this study was to examine the diagnostic value of structural MRI to distinguish depressive patients with and without ss using support vector machine. In this paper, we applied voxel-based morphometry of gray matter volume (GMV), then choose discriminative features to classify different group using linear support vector machine (SVM) classifier. The experimental results showed that specific structural brain regions may be a potential biomarkers for disease diagnosis.

引用

页码：63 / 67

页数：5

共 8 条

[1] A fast diffeomorphic image registration algorithm
Ashburner, John
[J]. NEUROIMAGE, 2007, 38 (01) : 95 - 113
[2] Boser B. E., 1992, Proceedings of the Fifth Annual ACM Workshop on Computational Learning Theory, P144, DOI 10.1145/130385.130401
[3] LIBSVM: A Library for Support Vector Machines
Chang, Chih-Chung
Lin, Chih-Jen
[J]. ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY, 2011, 2 (03)
[4] Chen YW, 2006, STUD FUZZ SOFT COMP, V207, P315
[5] SUPPORT-VECTOR NETWORKS
CORTES, C
VAPNIK, V
[J]. MACHINE LEARNING, 1995, 20 (03) : 273 - 297
[6] Cerebral asymmetry and the effects of sex and handedness on brain structure: A voxel-based morphometric analysis of 465 normal adult human brains
Good, CD
Johnsrude, I
Ashburner, J
Henson, RNA
Friston, KJ
Frackowiak, RSJ
[J]. NEUROIMAGE, 2001, 14 (03) : 685 - 700
[7] Structural Brain Changes in Patients with Recurrent Major Depressive Disorder Presenting with Anxiety Symptoms
Inkster, Becky
Rao, Anil W.
Ridler, Khanum
Nichols, Thomas E.
Saemann, Philipp G.
Auer, Dorothee P.
Holsboer, Florian
Tozzi, Federica
Muglia, Pierandrea
Merlo-Pich, Emilio
Matthews, Paul M.
[J]. JOURNAL OF NEUROIMAGING, 2011, 21 (04) : 375 - 382
[8] Regional Brain Volume in Depression and Anxiety Disorders
van Tol, Marie-Jose
van der Wee, Nic J. A.
van den Heuvel, Odile A.
Nielen, Marjan M. A.
Demenescu, Liliana R.
Aleman, Andre
Renken, Remco
van Buchem, Mark A.
Zitman, Frans G.
Veltman, Dick J.
[J]. ARCHIVES OF GENERAL PSYCHIATRY, 2010, 67 (10) : 1002 - 1011

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