Successful treatment of human granulocytic ehrlichiosis in children using rifampin

被引：37

作者：

Krause, PJ

Corrow, CL

Bakken, JS ^{[1
]}

机构：

[1] St Marys Duluth Clin Hlth Syst, Infect Dis Sect, Duluth, MN 55605 USA

[2] Univ Connecticut, Sch Med, Dept Pediat, Hartford, CT 06112 USA

[3] Connecticut Childrens Med Ctr, Hartford, CT USA

来源：

PEDIATRICS | 2003年 / 112卷 / 03期

关键词：

human granulocytic ehrlichiosis; HGE; A phagocytophilum; rifampin;

D O I：

10.1542/peds.112.3.e252

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Human granulocytic ehrlichiosis (HGE) is an emerging tick-borne infectious disease caused by Anaplasma phagocytophilum. Clinical features include a flu-like illness that usually resolves within 1 week. More serious infection may occur that requires hospital admission or culminates in death. Doxycycline is the treatment of choice for HGE but may cause permanent staining of teeth in children younger than 8 years of age. We report successful treatment of HGE with rifampin in 2 children, 4 and 6 years old. A course of rifampin for 5 to 7 days should be considered in children younger than 8 years of age who experience non-life-threatening A phagocytophilum infection.

引用

收藏

页码：E252 / E253

页数：2

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