Impact of glucose tolerance status on the development of coronary artery disease among working-age men

被引：32
作者：
Fujihara, K. [1 ]
Igarashi, R. [1 ]
Yamamoto, M. [1 ]
Ishizawa, M. [2 ]
Matsubayasi, Y. [1 ]
Matsunaga, S. [1 ]
Kato, K. [1 ]
Ito, C. [2 ]
Koishi, M. [2 ]
Yamanaka, N. [2 ]
Kodama, S. [1 ]
Sone, H. [1 ]
机构：
[1] Niigata Univ, Fac Med, Dept Internal Med, 1-754 Asahimachi, Niigata, Niigata 9518510, Japan
[2] Japan Med Data Ctr Co Ltd, Tokyo, Japan
来源：
DIABETES & METABOLISM | 2017年 / 43卷 / 03期
关键词：
Coronary artery disease; Glucose tolerance status; Working-age men; CARDIOVASCULAR-DISEASE; MYOCARDIAL-INFARCTION; DIABETES-MELLITUS; RISK-FACTORS; WOMEN; COMPLICATIONS; DATABASE; COHORT;
D O I：
10.1016/j.diabet.2016.09.001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Aims. To examine the impact of glucose tolerance status on the development of coronary artery disease (CAD) in working-age men in Japan. Methods. This population-based retrospective cohort study included 111,621 men aged 31-60 years [63,558 with normal glucose tolerance (NGT); 37,126 with prediabetes; 10,937 with diabetes]. The Cox proportional-hazards regression model was used to identify variables related to the incidence of CAD. Results. Multivariate analysis showed that, compared with NGT, diabetes increased the risk of CAD by 17.3 times (95% CI: 6.36-47.0) at ages 31-40 years, by 2.74 times (95% CI: 1.85-4.05) at ages 41-50 years and by 2.47 times (95% CI: 1.69-3.59) at ages 51-60 years. The HRs for CAD in men with diabetes aged 31-40 equaled that of men with NGT aged 51-60 [18.2 (7.15-46.4) and 19.4 (8.28-45.4), respectively]. Conclusion. The impact of diabetes on CAD was markedly greater in men aged 31-40 years compared with those aged 41-60 years. (C) 2016 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：261 / 264
页数：4
相关论文
共 13 条
[1]   Risk factors for myocardial infarction in women and men: insights from the INTERHEART study [J].
Anand, Sonia S. ;
Islam, Shofiqul ;
Rosengren, Annika ;
Franzosi, Maria Grazia ;
Steyn, Krisela ;
Yusufali, Afzal Hussein ;
Keltai, Matyas ;
Diaz, Rafael ;
Rangarajan, Sumathy ;
Yusuf, Salim .
EUROPEAN HEART JOURNAL, 2008, 29 (07) :932-940
[2]   Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus, impaired fasting glucose, and impaired glucose tolerance - The Australian diabetes, obesity, and lifestyle study (AusDiab) [J].
Barr, Elizabeth L. M. ;
Zimmet, Paul Z. ;
Welborn, Timothy A. ;
Jolley, Damien ;
Magliano, Dianna J. ;
Dunstan, David W. ;
Cameron, Adrian J. ;
Dwyer, Terry ;
Taylor, Hugh R. ;
Tonkin, Andrew M. ;
Wong, Tien Y. ;
McNeil, John ;
Shaw, Jonathan E. .
CIRCULATION, 2007, 116 (02) :151-157
[3]   Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study [J].
Booth, Gillian L. ;
Kapral, Moira K. ;
Fung, Kinwah ;
Tu, Jack V. .
LANCET, 2006, 368 (9529) :29-36
[4]   Pre-Diabetes and the Risk for Cardiovascular Disease A Systematic Review of the Evidence [J].
Ford, Earl S. ;
Zhao, Guixiang ;
Li, Chaoyang .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 55 (13) :1310-1317
[5]   Changes in Diabetes-Related Complications in the United States, 1990-2010 [J].
Gregg, Edward W. ;
Li, Yanfeng ;
Wang, Jing ;
Burrows, Nilka Rios ;
Ali, Mohammed K. ;
Rolka, Deborah ;
Williams, Desmond E. ;
Geiss, Linda .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (16) :1514-1523
[6]   The metabolic syndrome: Time for a critical appraisal - Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes [J].
Kahn, R ;
Buse, J ;
Ferrannini, E ;
Stern, M .
DIABETES CARE, 2005, 28 (09) :2289-2304
[7]   Development of a Database of Health Insurance Claims: Standardization of Disease Classifications and Anonymous Record Linkage [J].
Kimura, Shinya ;
Sato, Toshihiko ;
Ikeda, Shunya ;
Noda, Mitsuhiko ;
Nakayama, Takeo .
JOURNAL OF EPIDEMIOLOGY, 2010, 20 (05) :413-419
[8]   Risk of myocardial infarction in men and women with type 2 diabetes in the UK: a cohort study using the General Practice Research Database [J].
Mulnier, H. E. ;
Seaman, H. E. ;
Raleigh, V. S. ;
Soedamah-Muthu, S. S. ;
Colhoun, H. M. ;
Lawrenson, R. A. ;
de Vries, C. S. .
DIABETOLOGIA, 2008, 51 (09) :1639-1645
[9]  
Sarwar N, 2010, LANCET, V375, P2215, DOI 10.1016/S0140-6736(10)60484-9
[10]   Serum Level of Triglycerides Is a Potent Risk Factor Comparable to LDL Cholesterol for Coronary Heart Disease in Japanese Patients with Type 2 Diabetes: Subanalysis of the Japan Diabetes Complications Study (JDCS) [J].
Sone, Hirohito ;
Tanaka, Sachiko ;
Tanaka, Shiro ;
Iimuro, Satoshi ;
Oida, Koji ;
Yamasaki, Yoshimitsu ;
Oikawa, Shinichi ;
Ishibashi, Shun ;
Katayama, Shigehiro ;
Ohashi, Yasuo ;
Akanuma, Yasuo ;
Yamada, Nobuhiro .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2011, 96 (11) :3448-3456
12