Respiratory syncytial virus outbreak defined by rapid screening in a neonatal intensive care unit

被引：38

作者：

Dizdar, E. A. ^{[1
]}

Aydemir, C. ^{[1
]}

Erdeve, O. ^{[1
]}

Sari, F. N. ^{[1
]}

Oguz, S. ^{[1
]}

Uras, N. ^{[1
]}

Dilmen, U. ^{[1
]}

机构：

[1] Zekai Tahir Burak Womens Hlth & Educ Hosp, Neonatal Intens Care Unit, TR-06111 Ankara, Turkey

来源：

JOURNAL OF HOSPITAL INFECTION | 2010年 / 75卷 / 04期

关键词：

Neonatal intensive care unit; Outbreak; Palivizumab; Rapid screening test; Respiratory syncytial virus; INFECTION; PALIVIZUMAB; INFANTS; DISEASE;

D O I：

10.1016/j.jhin.2010.01.013

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Palivizumab is currently licensed for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease in infants and children with chronic lung disease, with a history of preterm birth, or with haemodynamically significant congenital heart disease, but its routine use during outbreaks in neonatal intensive care units (NICUs) is not currently recommended. Here we report an outbreak in a NICU detected during a screening trial for RSV infection using a rapid antigen test (Respi-Strip (R)). Eleven preterm infants in our NICU tested positive for RSV during January 2009. Subsequent testing of the remaining infants in the NICU revealed two additional asymptomatic cases. In addition to precautions against cross-infection, palivizumab prophylaxis was administered to the remaining 37 premature infants. Two days after treatment, RSV was detected in two additional infants who had become symptomatic. To our knowledge this is the largest RSV outbreak in a NICU to be identified at an early stage by rapid testing and effectively controlled by infection control measures and palivizumab prophylaxis. (C) 2010 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：292 / 294

页数：3

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