Therapy of rheumatoid arthritis by blocking IL-6 signal transduction with a humanized anti-IL-6 receptor antibody

被引：100
作者：
Yoshizaki, K
Nishimoto, N
Mihara, M
Kishimoto, T
机构：
[1] Osaka Univ, Sch hlth & Sports Sci, Dept Med Sci 1, Suita, Osaka 5650871, Japan
[2] Chugai Pharmaceut Co Ltd, Fuji Gotenba Labs, Shizuoka, Japan
来源：
SPRINGER SEMINARS IN IMMUNOPATHOLOGY | 1998年 / 20卷 / 1-2期
关键词：
D O I：
10.1007/s002810050033
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：247 / 259
页数：13
相关论文
共 71 条
[1]   RECOMBINANT HUMAN B-CELL STIMULATORY FACTOR-II (BSF-2/IFN-BETA2) REGULATES BETA-FIBRINOGEN AND ALBUMIN MESSENGER-RNA LEVELS IN FAO-9 CELLS [J].
ANDUS, T ;
GEIGER, T ;
HIRANO, T ;
NORTHOFF, H ;
GANTER, U ;
BAUER, J ;
KISHIMOTO, T ;
HEINRICH, PC .
FEBS LETTERS, 1987, 221 (01) :18-22
[2]  
ASANO S, 1990, BLOOD, V75, P1602
[3]   COLLAGEN-INDUCED ARTHRITIS IN AN OUTBRED GROUP OF RHESUS-MONKEYS COMPRISING RESPONDER AND NONRESPONDER ANIMALS - RELATIONSHIP BETWEEN THE COURSE OF ARTHRITIS AND COLLAGEN-SPECIFIC IMMUNITY [J].
BAKKER, NPM ;
VANERCK, MGM ;
BOTMAN, CAD ;
JONKER, M ;
THART, BA .
ARTHRITIS AND RHEUMATISM, 1991, 34 (05) :616-624
[4]   Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis [J].
Campion, GV ;
Lebsack, ME ;
Lookabaugh, J ;
Gordon, G ;
Catalano, M ;
Borenstein, D ;
Caldwell, J ;
Cohen, SA ;
Cohen, SB ;
Fleischmann, R ;
Heller, MD ;
Howard, P ;
Jaffer, AM ;
Kaine, JL ;
Kitsis, E ;
Kopp, EJ ;
Moreland, LW ;
OHanlan, M ;
Prupas, M ;
Rosenberg, A ;
Rutstein, J ;
Sack, MR ;
Schiff, MH ;
Singleton, CM ;
Taborn, J ;
Tindall, E ;
Weaver, AL ;
Yocum, D .
ARTHRITIS AND RHEUMATISM, 1996, 39 (07) :1092-1101
[5]   RECOMBINANT HUMAN INTERLEUKIN-6 (IL-6/BSF-2/HSF) REGULATES THE SYNTHESIS OF ACUTE PHASE PROTEINS IN HUMAN HEPATOCYTES [J].
CASTELL, JV ;
GOMEZLECHON, MJ ;
DAVID, M ;
HIRANO, T ;
KISHIMOTO, T ;
HEINRICH, PC .
FEBS LETTERS, 1988, 232 (02) :347-350
[6]  
CATHCART ES, 1986, LAB INVEST, V54, P26
[7]  
CEUPPENS JL, 1988, J IMMUNOL, V141, P3868
[8]   IMMUNIZATION AGAINST HETEROLOGOUS TYPE-II COLLAGEN INDUCES ARTHRITIS IN MICE [J].
COURTENAY, JS ;
DALLMAN, MJ ;
DAYAN, AD ;
MARTIN, A ;
MOSEDALE, B .
NATURE, 1980, 283 (5748) :666-668
[9]   RANDOMIZED DOUBLE-BLIND COMPARISON OF CHIMERIC MONOCLONAL-ANTIBODY TO TUMOR-NECROSIS-FACTOR-ALPHA (CA2) VERSUS PLACEBO IN RHEUMATOID-ARTHRITIS [J].
ELLIOTT, MJ ;
MAINI, RN ;
FELDMANN, M ;
KALDEN, JR ;
ANTONI, C ;
SMOLEN, JS ;
LEEB, B ;
BREEDVELD, FC ;
MACFARLANE, JD ;
BIJL, H ;
WOODY, JN .
LANCET, 1994, 344 (8930) :1105-1110
[10]  
Evans James, 1997, Arthritis and Rheumatism, V40, pS224
12345678