Challenges in pulmonary fibrosis • 5:: The NSIP/UIP debate

被引：59

作者：

du Bois, Roland

King, Talmadge E., Jr.

机构：

[1] Univ Calif San Francisco, Dept Med, San Francisco, CA 94110 USA

[2] Imperial Coll Sci, Natl Heart & Lung Inst, Dept Occupat & Environm Med, Interstitial Lung Dis Unit, London, England

来源：

THORAX | 2007年 / 62卷 / 11期

关键词：

D O I：

10.1136/thx.2004.031039

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Among the idiopathic interstitial pneumonias, the two entities idiopathic pulmonary fibrosis (IPF) characterised by the presence of the usual interstitial pneumonia pattern of histopathology (IPF/UIP) and non-specific interstitial pneumonia (NSIP; same nomenclature for the histopathological pattern and idiopathic disease)-have provoked considerable debate. IPF/UIP and NSIP closely mimic each other clinically but NSIP has a far better outcome. However, it remains unclear if NSIP is a truly separate and distinct entity. The histopathological pattern of NSIP can be found in a wide variety of clinical and radiological contexts. This review addresses these and other uncertainties regarding NSIP and UIP.

引用

页码：1008 / 1012

页数：5

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