LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family

被引：41

作者：

Chiosis, G ^{[1
]}

Rosen, N ^{[1
]}

Sepp-Lorenzino, L ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Mol Oncogenesis, New York, NY 10021 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 07期

关键词：

D O I：

10.1016/S0960-894X(01)00099-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Several LY294002-GM heterodimers were synthesized with the intent of modulating their activity in the presence of hsp90 and thereby creating selective inhibitors of PI3K and PI3K-related family. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：909 / 913

页数：5

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