Integrated approach of brachial-ankle pulse wave velocity and cardiovascular risk scores for predicting the risk of cardiovascular events

被引:6
作者
Kim, Hyue Mee [1 ]
Rhee, Tae-Min [2 ]
Kim, Hack-Lyoung [2 ]
机构
[1] Chung Ang Univ, Coll Med, Chung Ang Univ Hosp, Div Cardiol,Dept Internal Med, Seoul, South Korea
[2] Seoul Natl Univ, Coll Med, Boramae Med Ctr, Div Cardiol,Dept Internal Med, Seoul, South Korea
来源
PLOS ONE | 2022年 / 17卷 / 04期
关键词
CORONARY-HEART-DISEASE; ARTERIAL STIFFNESS; METABOLIC SYNDROME; AMERICAN-COLLEGE; PROGNOSTIC VALUE; ATHEROSCLEROSIS; MORTALITY; STROKE; IMPACT; INDEX;
D O I
10.1371/journal.pone.0267614
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) atherosclerotic cardiovascular disease (ASCVD) risk score may be insufficient for accurate prediction of major adverse cardiac events (MACE) in Asians. This study was performed to investigate whether brachial-ankle pulse wave velocity (baPWV) has additional prognostic value to the risk score estimated by the ACC/AHA pooled cohort equations (PCEs). Methods A total of 6,359 patients (3,534 men and 2,825 women) aged 40-79 years without documented cardiovascular disease who underwent baPWV measurement were retrospectively analyzed. Cardiovascular risk scores were calculated using the 2013 ACC/AHA PCEs. Cardiovascular events, including cardiac death, non-fatal myocardial infarction, coronary revascularization and ischemic stroke, were assessed. Results During a median follow-up period of 4.0 years (interquartile range 1.7-6.1 years), cardiovascular events occurred in 129 patients (2.0%). The receiver operating characteristic curve analysis showed that baPWV was stronger in the detection of cardiovascular events than the 2013 ACC/AHA risk score (area under the curve: 0.70 versus 0.62, p<0.001). In the multivariable Cox regression analysis, both baPWV and 2013 ACC/AHA risk score were independently associated with the occurrence of clinical events (p <0.001 for each). The baPWV had incremental prognostic value to the 2013 ACC/AHA risk score in predicting clinical events (global chi-square from 21.23 to 49.51, p<0.001). Conclusion The baPWV appears to be a strong predictor of the risk of cardiovascular events in Koreans. Measuring baPWV in addition to the 2013 ACC/AHA risk score helps identify individuals at risk for MACE aged 40-79 years without previous cardiovascular diseases.
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页数:12
相关论文
共 39 条
  • [1] Arnett DK, 2019, CIRCULATION, V140, pE596, DOI [10.1161/CIR.0000000000000677, 10.1016/j.jacc.2019.03.010, 10.1161/CIR.0000000000000678, 10.1016/j.jacc.2019.03.009]
  • [2] Pitfalls in the ankle-brachial index and brachial-ankle pulse wave velocity
    Ato, Dai
    [J]. VASCULAR HEALTH AND RISK MANAGEMENT, 2018, 14 : 41 - 62
  • [3] Aortic Stiffness Current Understanding and Future Directions
    Cavalcante, Joao L.
    Lima, Joao A. C.
    Redheuil, Alban
    Al-Mallah, Mouaz H.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 57 (14) : 1511 - 1522
  • [4] General cardiovascular risk profile for use in primary care - The Framingham Heart Study
    D'Agostino, Ralph B.
    Vasan, Ramachandran S.
    Pencina, Michael J.
    Wolf, Philip A.
    Cobain, Mark
    Massaro, Joseph M.
    Kannel, William B.
    [J]. CIRCULATION, 2008, 117 (06) : 743 - 753
  • [5] Risk score overestimation: the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort
    DeFilippis, Andrew Paul
    Young, Rebekah
    McEvoy, John W.
    Michos, Erin D.
    Sandfort, Veit
    Kronmal, Richard A.
    McClelland, Robyn L.
    Blaha, Michael J.
    [J]. EUROPEAN HEART JOURNAL, 2017, 38 (08) : 598 - 608
  • [6] COMPARING THE AREAS UNDER 2 OR MORE CORRELATED RECEIVER OPERATING CHARACTERISTIC CURVES - A NONPARAMETRIC APPROACH
    DELONG, ER
    DELONG, DM
    CLARKEPEARSON, DI
    [J]. BIOMETRICS, 1988, 44 (03) : 837 - 845
  • [7] 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    Goff, David C., Jr.
    Lloyd-Jones, Donald M.
    Bennett, Glen
    Coady, Sean
    D'Agostino, Ralph B., Sr.
    Gibbons, Raymond
    Greenland, Philip
    Lackland, Daniel T.
    Levy, Daniel
    O'Donnell, Christopher J.
    Robinson, Jennifer G.
    Schwartz, J. Sanford
    Shero, Susan T.
    Smith, Sidney C., Jr.
    Sorlie, Paul
    Stone, Neil J.
    Wilson, Peter W. F.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 63 (25) : 2935 - 2959
  • [8] Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report
    Grundy, SM
    Becker, D
    Clark, LT
    Cooper, RS
    Denke, MA
    Howard, WJ
    Hunninghake, DB
    Illingworth, R
    Luepker, RV
    McBride, P
    McKenney, JM
    Pasternak, RC
    Stone, NJ
    Van Horn, L
    Brewer, HB
    Cleeman, JI
    Ernst, ND
    Gordon, D
    Levy, D
    Rifkind, B
    Rossouw, JE
    Savage, P
    Haffner, SM
    Orloff, DG
    Proschan, MA
    Schwartz, JS
    Sempos, CT
    Shero, ST
    Murray, EZ
    Keller, SA
    Jehle, AJ
    [J]. CIRCULATION, 2002, 106 (25) : 3143 - 3421
  • [9] Guerin AP, 2001, CIRCULATION, V103, P987
  • [10] Systematic Review of Health Disparities for Cardiovascular Diseases and Associated Factors among American Indian and Alaska Native Populations
    Hutchinson, Rebecca Newlin
    Shin, Sonya
    [J]. PLOS ONE, 2014, 9 (01):