Graphene substrates promote adherence of human osteoblasts and mesenchymal stromal cells

被引：398

作者：

Kalbacova, Marie ^{[2
]}

Broz, Antonin ^{[2
]}

Kong, Jing ^{[3
]}

Kalbac, Martin ^{[1
,4
]}

机构：

[1] Acad Sci Czech Republ, J Heyrovsky Inst Phys Chem Vvi, CR-18223 Prague 8, Czech Republic

[2] Charles Univ Prague, Fac Med 1, Inst Inherited Metab Disorders, Prague 12808 2, Czech Republic

[3] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA

[4] Palacky Univ, Dept Phys Chem, Olomouc 77146, Czech Republic

来源：

CARBON | 2010年 / 48卷 / 15期

基金：

美国国家科学基金会;

关键词：

LARGE-AREA; FILMS; ATTACHMENT; NANOTUBES; ADHESION; SAOS-2; SHAPE;

D O I：

10.1016/j.carbon.2010.07.045

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The biocompatibility of large single layer graphene produced by chemical vapour deposition was investigated using human osteoblasts and mesenchymal stromal cells. The study was focused on cellular adhesion, morphology and the ability to proliferate on graphene substrates. It was found that both of the cell types which were tested adhered and proliferated better when cultured on graphene films than on a SiO2 substrate. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：4323 / 4329

页数：7

共 32 条

[1] Thin films of single-walled carbon nanotubes promote human osteoblastic cells (Saos-2) proliferation in low serum concentrations [J].

Akasaka, Tsukasa ;

Yokoyama, Atsuro ;

Matsuoka, Makoto ;

Hashimoto, Takeshi ;

Watari, Fumio .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2010, 30 (03) :391-399

[2] The influence of microscale topography on fibroblast attachment and motility [J].

Berry, CC ;

Campbell, G ;

Spadiccino, A ;

Robertson, M ;

Curtis, ASG .

BIOMATERIALS, 2004, 25 (26) :5781-5788

[3] Electromechanical resonators from graphene sheets [J].

Bunch, J. Scott ;

van der Zande, Arend M. ;

Verbridge, Scott S. ;

Frank, Ian W. ;

Tanenbaum, David M. ;

Parpia, Jeevak M. ;

Craighead, Harold G. ;

McEuen, Paul L. .

SCIENCE, 2007, 315 (5811) :490-493

[4] Graphene Fluorescence Resonance Energy Transfer Aptasensor for the Thrombin Detection [J].

Chang, Haixin ;

Tang, Longhua ;

Wang, Ying ;

Jiang, Jianhui ;

Li, Jinghong .

ANALYTICAL CHEMISTRY, 2010, 82 (06) :2341-2346

[5] Geometric control of cell life and death [J].

Chen, CS ;

Mrksich, M ;

Huang, S ;

Whitesides, GM ;

Ingber, DE .

SCIENCE, 1997, 276 (5317) :1425-1428

[6] Transmembrane extracellular matrix-cytoskeleton crosstalk [J].

Geiger, B ;

Bershadsky, A ;

Pankov, R ;

Yamada, KM .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (11) :793-805

[7] Environmental sensing through focal adhesions [J].

Geiger, Benjamin ;

Spatz, Joachim P. ;

Bershadsky, Alexander D. .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2009, 10 (01) :21-33

[8] Transduction - Integrin signaling [J].

Giancotti, FG ;

Ruoslahti, E .

SCIENCE, 1999, 285 (5430) :1028-1032

[9] Response of osteoblast-like SAOS-2 cells to zirconia ceramics with different surface topographies [J].

Hempel, Ute ;

Hefti, Thomas ;

Kalbacova, Marie ;

Wolf-Brandstetter, Cornelia ;

Dieter, Peter ;

Schlottig, Falko .

CLINICAL ORAL IMPLANTS RESEARCH, 2010, 21 (02) :174-181

[10] Integrins: Bidirectional, allosteric signaling machines [J].

Hynes, RO .

CELL, 2002, 110 (06) :673-687

← 1 2 3 4 →