gem-dibromomethylarenes:: A convenient substitute for noncommercial aldehydes in the Knoevenagel-Doebner reaction for the synthesis of α,β-unsaturated carboxylic acids

被引：59
作者：
Augustine, John Kallikat
Naik, Yanjerappa Arthoba
Mandal, Ashis Baran
Chowdappa, Nagaraja
Praveen, Vinuthan B.
机构：
[1] Syngene Int Ltd, Bangalore 560100, Karnataka, India
[2] Kuvempu Univ, Dept Chem, Shimoga 577451, India
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 25期
关键词：
D O I：
10.1021/jo701888m
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[Graphics] A facile synthesis of alpha,beta-unsaturated carboxylic acids from gem-dibromomethylarenes is described. gem-Dibromomethylarenes are employed for the first time in the Knoevenagel-Doebner reaction as aldehyde equivalents for the efficient synthesis of alpha,beta-unsaturated carboxylic acids.
引用
收藏
页码：9854 / 9856
页数：3
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