gem-dibromomethylarenes:: A convenient substitute for noncommercial aldehydes in the Knoevenagel-Doebner reaction for the synthesis of α,β-unsaturated carboxylic acids

被引：59

作者：

Augustine, John Kallikat

Naik, Yanjerappa Arthoba

Mandal, Ashis Baran

Chowdappa, Nagaraja

Praveen, Vinuthan B.

机构：

[1] Syngene Int Ltd, Bangalore 560100, Karnataka, India

[2] Kuvempu Univ, Dept Chem, Shimoga 577451, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 25期

关键词：

D O I：

10.1021/jo701888m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[Graphics] A facile synthesis of alpha,beta-unsaturated carboxylic acids from gem-dibromomethylarenes is described. gem-Dibromomethylarenes are employed for the first time in the Knoevenagel-Doebner reaction as aldehyde equivalents for the efficient synthesis of alpha,beta-unsaturated carboxylic acids.

引用

页码：9854 / 9856

页数：3

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