Medical Prevention of Breast Cancer

被引：11
|
作者：
Stubert, Johannes [1 ]
Dieterich, Max [1 ]
Gerber, Bernd [1 ]
机构：
[1] Univ Rostock, Dept Obstet & Gynecol, D-18059 Rostock, Germany
来源：
BREAST CARE | 2014年 / 9卷 / 06期
关键词：
Breast cancer; Prevention; Tamoxifen; SERMs; Aromatase inhibitors; SURGICAL ADJUVANT BREAST; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; BONE-MINERAL DENSITY; POSTMENOPAUSAL WOMEN; RANDOMIZED-TRIAL; BOWEL PROJECT; CLINICAL-TRIALS; FAMILY-HISTORY; FOLLOW-UP; RISK;
D O I：
10.1159/000369573
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Breast cancer is the most common cancer of women in Western Europe and North America. Effective strategies of medical prevention could reduce the burden of breast cancer mortality. The best evidence for a risk reduction exists for hormonal agents such as tamoxifen and raloxifene (22-72%) or aromatase inhibitors (50-65%). However, the severity of side effects and the lack of evidence for an improved survival compromise the risk/benefit balance. In this review the results of chemoprevention studies, including new treatment approaches, are summarized with critical discussion of their use in clinical practice.
引用
收藏
页码：391 / 396
页数：6
相关论文
共 50 条
  • [21] Breast Cancer Risk Assessment, Prevention, and the Future
    Green, Victoria L.
    OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA, 2013, 40 (03) : 525 - +
  • [22] BREAST CANCER PREVENTION: LIFESTYLE CHANGES AND CHEMOPREVENTION
    Lambrechts, S.
    Decloedt, J.
    Neven, P.
    ACTA CLINICA BELGICA, 2011, 66 (04) : 283 - 292
  • [23] Breast cancer chemoprevention
    Gabriel, Emmanuel M.
    Jatoi, Ismail
    EXPERT REVIEW OF ANTICANCER THERAPY, 2012, 12 (02) : 223 - 228
  • [24] Ongoing data from the breast cancer prevention trials: opportunity for breast cancer risk reduction
    Vogel, Victor G.
    BMC MEDICINE, 2015, 13
  • [25] Preventive Therapy for Breast Cancer
    Sestak, Ivana
    Cuzick, Jack
    CURRENT ONCOLOGY REPORTS, 2012, 14 (06) : 568 - 573
  • [26] Breast Cancer Prevention Trials: Large and Small Trials
    Arun, Banu
    Dunn, Barbara K.
    Ford, Leslie G.
    Ryan, Anne
    SEMINARS IN ONCOLOGY, 2010, 37 (04) : 367 - 383
  • [27] Breast cancer prevention in high-risk women
    Thorat, Mangesh A.
    Balasubramanian, Rajeshkumar
    BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 2020, 65 : 18 - 31
  • [28] The selective estrogen receptor modulators in breast cancer prevention
    Li, Fangxuan
    Dou, Jinli
    Wei, Lijuan
    Li, Shixia
    Liu, Juntian
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2016, 77 (05) : 895 - 903
  • [29] Breast cancer prevention with anti-estrogens: review of the current evidence and future directions
    Mallick, Supriya
    Benson, Rony
    Julka, P. K.
    BREAST CANCER, 2016, 23 (02) : 170 - 177
  • [30] Hormonal prevention of breast cancer
    Thomin, Anne
    Friszer, Stephanie
    Fajac, Anne
    Darai, Emile
    Chabbert-Buffet, Nathalie
    ANNALES D ENDOCRINOLOGIE, 2014, 75 (03) : 148 - 155
12345