Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen

被引：116

作者：

Ehrlich, Hermann ^{[1
]}

Deutzmann, Rainer ^{[2
]}

Brunner, Eike ^{[1
]}

Cappellini, Enrico ^{[3
]}

Koon, Hannah ^{[3
]}

Solazzo, Caroline ^{[3
]}

Yang, Yue ^{[3
]}

Ashford, David ^{[4
,5
]}

Thomas-Oates, Jane ^{[5
,6
]}

Lubeck, Markus ^{[7
]}

Baessmann, Carsten ^{[7
]}

Langrock, Tobias ^{[8
]}

Hoffmann, Ralf ^{[8
]}

Woerheide, Gert ^{[9
,10
]}

Reitner, Joachim ^{[11
]}

Simon, Paul ^{[12
]}

Tsurkan, Mikhail ^{[13
,14
]}

Ereskovsky, Aleksander V. ^{[15
,16
]}

Kurek, Denis ^{[1
,17
]}

Bazhenov, Vasily V. ^{[1
,18
]}

Hunoldt, Sebastian ^{[1
]}

Mertig, Michael ^{[19
,20
]}

Vyalikh, Denis V. ^{[21
,22
]}

Molodtsov, Serguei L. ^{[21
,22
]}

Kummer, Kurt ^{[21
,22
]}

Worch, Hartmut ^{[19
,20
]}

Smetacek, Victor ^{[23
]}

Collins, Matthew J. ^{[3
]}

机构：

[1] Tech Univ Dresden, Inst Bioanalyt Chem, D-01062 Dresden, Germany

[2] Univ Regensburg, Inst Biochem Genet & Microbiol, D-93053 Regensburg, Germany

[3] Univ York, Dept Biol, BioArCh, York YO10 5YW, N Yorkshire, England

[4] Univ York, Dept Biol, Technol Facil, York YO10 5YW, N Yorkshire, England

[5] Univ York, Ctr Excellence Mass Spectrometry, York YO10 5DD, N Yorkshire, England

[6] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

[7] Bruker Daltonik GmbH, D-28359 Bremen, Germany

[8] Univ Leipzig, Ctr Biotechnol & Biomed BBZ, Inst Bioanalyt Chem, D-014103 Leipzig, Germany

[9] Univ Munich, Dept Geo & Umweltwissensch, D-80333 Munich, Germany

[10] Univ Munich, GeoBioctr LMU, D-80333 Munich, Germany

[11] Univ Gottingen, Dept Geobiol, D-37077 Gottingen, Germany

[12] Max Planck Inst Chem Phys Solids, D-01187 Dresden, Germany

[13] Leibniz Inst Polymer Res Dresden, D-01005 Dresden, Germany

[14] Max Bergmann Ctr Biomat, D-01005 Dresden, Germany

[15] Aix Marseille Univ, Ctr Oceanol Marseille, Marine Endoume Stn, CNRS,UMR DIMAR 6540, F-13007 Marseille, France

[16] St Petersburg State Univ, St Petersburg 199034, Russia

[17] Russian Acad Sci, Ctr Bioengn, Moscow 117312, Russia

[18] Far Eastern Natl Univ, Inst Chem & Appl Ecol, Vladivostok 690650, Russia

[19] Tech Univ Dresden, Inst Mat Sci, D-01069 Dresden, Germany

[20] Tech Univ Dresden, Max Bergmann Ctr Biomat, D-01069 Dresden, Germany

[21] Tech Univ Dresden, Inst Solid State Phys, D-01069 Dresden, Germany

[22] European XFEL GmbH, D-22761 Hamburg, Germany

[23] Alfred Wegener Inst Polar & Marine Res, D-27570 Bremerhaven, Germany

来源：

NATURE CHEMISTRY | 2010年 / 2卷 / 12期

关键词：

DIATOM CELL-WALLS; AMINO-ACID; SPICULES; TISSUES; PROTEIN; SILICA;

D O I：

10.1038/NCHEM.899

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The minerals involved in the formation of metazoan skeletons principally comprise glassy silica, calcium phosphate or carbonate. Because of their ancient heritage, glass sponges (Hexactinellida) may shed light on fundamental questions such as molecular evolution, the unique chemistry and formation of the first skeletal silica-based structures, and the origin of multicellular animals. We have studied anchoring spicules from the metre-long stalk of the glass rope sponge (Hyalonema sieboldi; Porifera, Class Hexactinellida), which are remarkable for their size, durability, flexibility and optical properties. Using slow-alkali etching of biosilica, we isolated the organic fraction, which was revealed to be dominated by a hydroxylated fibrillar collagen that contains an unusual [Gly-3Hyp-4Hyp] motif. We speculate that this motif is predisposed for silica precipitation, and provides a novel template for biosilicification in nature.

引用

页码：1084 / 1088

页数：5

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