Function of Protein Phosphatase-1, Glc7, in Saccharomyces cerevisiae

被引：35

作者：

Cannon, John F. ^{[1
]}

机构：

[1] Univ Missouri, Dept Mol Microbiol & Immunol, Columbia, MO 65211 USA

来源：

ADVANCES IN APPLIED MICROBIOLOGY, VOL 73 | 2010年 / 73卷

关键词：

AURORA B KINASE; KINETOCHORE-MICROTUBULE ATTACHMENTS; MITOTIC CELL-CYCLE; NUCLEAR-LOCALIZATION; BUDDING YEAST; CHROMOSOME SEGREGATION; SEPTIN ORGANIZATION; SPINDLE CHECKPOINT; ACTIN ORGANIZATION; GLUCOSE REPRESSION;

D O I：

10.1016/S0065-2164(10)73002-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Budding yeast, Saccharomyces cerevisiae, and its close relatives are unique among eukaryotes in having a single gene, GLC7, encoding protein phosphatase-1 (PP1). This enzyme with a highly conserved amino acid sequence controls many processes in all eukaryotic cells. Therefore, the study of Glc7 function offers a unique opportunity to gain a comprehensive understanding of this critical regulatory enzyme. This review summarizes our current knowledge of how Glc7 function modulates processes in the cytoplasm and nucleus. Additionally, global Glc7 regulation is described.

引用

页码：27 / 59

页数：33

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