Parallel synthesis of terminal alkynes using a ROMPgel-supported ethyl 1-diazo-2-oxopropylphosphonate

被引:46
作者
Barrett, AGM [1 ]
Hopkins, BT [1 ]
Love, AC [1 ]
Tedeschi, L [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AZ, England
关键词
D O I
10.1021/ol049915z
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
ROMPgel-supported ethyl 1-diazo-2-oxopropylphosphonate has been prepared, and the supported reagent has been effectively employed in the conversion of a variety of aldehydes into terminal alkynes under mild reaction conditions. The influence of cross-link structure, comonomers, and polymer structure on reaction efficiency has been examined.
引用
收藏
页码:835 / 837
页数:3
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