Role of Sex Hormones in the Development of Osteoarthritis

被引:39
|
作者
Linn, Sarah [1 ]
Murtaugh, Bryan [1 ]
Casey, Ellen [1 ]
机构
[1] Rehabil Inst Chicago, Dept Phys Med & Rehabil, Chicago, IL 60611 USA
关键词
ESTROGEN REPLACEMENT THERAPY; KNEE CARTILAGE VOLUME; ARTICULAR CHONDROCYTES; POSTMENOPAUSAL WOMEN; OVARIECTOMIZED RATS; ASSOCIATION; ESTRADIOL; RISK; HAND; HIP;
D O I
10.1016/j.pmrj.2012.01.013
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Women older than 50 years have a considerably higher prevalence of osteoarthritis than men of the same age group. Although several factors have been proposed, there is some evidence that sex hormones influence the development of osteoarthritis. This article will focus on the basic science and clinical evidence that describe the current state of knowledge regarding the relationship between sex hormones and the development of osteoarthritis. PM R 2012;4:S169-S173
引用
收藏
页码:S169 / S173
页数:5
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