Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

被引：43
作者：
Franks, Stephen [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Inst Reprod & Dev Biol, Hammersmith Hosp, London W12 0NN, England
来源：
ENDOCRINOLOGY | 2012年 / 153卷 / 06期
基金：
英国医学研究理事会;
关键词：
FEMALE RHESUS-MONKEYS; MEDICAL PROGRESS; SYNDROME PCOS; FETAL; PATHOGENESIS; WOMEN; TESTOSTERONE; FOLLICLES; SHEEP;
D O I：
10.1210/en.2012-1366
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2536 / 2538
页数：3
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共 33 条
  • [1] Fetal, Infant, Adolescent and Adult Phenotypes of Polycystic Ovary Syndrome in Prenatally Androgenized Female Rhesus Monkeys
    Abbott, David H.
    Tarantal, Alice F.
    Dumesic, Daniel A.
    [J]. AMERICAN JOURNAL OF PRIMATOLOGY, 2009, 71 (09) : 776 - 784
  • [2] Developmental origin of polycystic ovary syndrome - a hypothesis
    Abbott, DH
    Dumesic, DA
    Franks, S
    [J]. JOURNAL OF ENDOCRINOLOGY, 2002, 174 (01) : 1 - 5
  • [3] Insights into the development of polycystic ovary syndrome (PCOS) from studies of prenatally androgenized female rhesus monkeys
    Abbott, DH
    Dumesic, DA
    Eisner, JR
    Colman, RJ
    Kemnitz, JW
    [J]. TRENDS IN ENDOCRINOLOGY AND METABOLISM, 1998, 9 (02) : 62 - 67
  • [4] Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: Associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition
    Barber, Thomas M.
    Hazell, Matthew
    Christodoulides, Constantinos
    Golding, Stephen J.
    Alvey, Christopher
    Burling, Keith
    Vidal-Puig, Antonio
    Groome, Nigel P.
    Wass, John A. H.
    Franks, Stephen
    McCarthy, Mark I.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (07) : 2859 - 2865
  • [5] Prenatal programming of reproductive neuroendocrine function: Fetal androgen exposure produces progressive disruption of reproductive cycles in sheep
    Birch, RA
    Padmanabhan, V
    Foster, DL
    Unsworth, WP
    Robinson, JE
    [J]. ENDOCRINOLOGY, 2003, 144 (04) : 1426 - 1434
  • [6] Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3
    Chen, Zi-Jiang
    Zhao, Han
    He, Lin
    Shi, Yuhua
    Qin, Yingying
    Shi, Yongyong
    Li, Zhiqiang
    You, Li
    Zhao, Junli
    Liu, Jiayin
    Liang, Xiaoyan
    Zhao, Xiaoming
    Zhao, Junzhao
    Sun, Yingpu
    Zhang, Bo
    Jiang, Hong
    Zhao, Dongni
    Bian, Yuehong
    Gao, Xuan
    Geng, Ling
    Li, Yiran
    Zhu, Dongyi
    Sun, Xiuqin
    Xu, Jin-e
    Hao, Cuifang
    Ren, Chun-e
    Zhang, Yajie
    Chen, Shiling
    Zhang, Wei
    Yang, Aijun
    Yan, Junhao
    Li, Yuan
    Ma, Jinlong
    Zhao, Yueran
    [J]. NATURE GENETICS, 2011, 43 (01) : 55 - U75
  • [7] Human fetal ovary development involves the spatiotemporal expression of P450c17 protein
    Cole, Beth
    Hensinger, Krista
    Maciel, Gustavo A. R.
    Chang, R. Jeffery
    Erickson, Gregory F.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (09) : 3654 - 3661
  • [8] Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
    Dunaif, A
    [J]. ENDOCRINE REVIEWS, 1997, 18 (06) : 774 - 800
  • [9] Medical progress: Polycystic ovary syndrome
    Ehrmann, DA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (12) : 1223 - 1236
  • [10] Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group
    Fauser, Bart C. J. M.
    Tarlatzis, Basil C.
    Rebar, Robert W.
    Legro, Richard S.
    Balen, Adam H.
    Lobo, Roger
    Carmina, Enrico
    Chang, Jeffrey
    Yildiz, Bulent O.
    Laven, Joop S. E.
    Boivin, Jacky
    Petraglia, Felice
    Wijeyeratne, C. N.
    Norman, Robert J.
    Dunaif, Andrea
    Franks, Stephen
    Wild, Robert A.
    Dumesic, Daniel
    Barnhart, Kurt
    [J]. FERTILITY AND STERILITY, 2012, 97 (01) : 28 - U84
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