A facile synthesis of novel 9-substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones

被引：3

作者：

Deredas, Dariusz ^{[1
]}

Lagiewka, Bartosz ^{[1
]}

Maniukiewicz, Waldemar ^{[2
]}

机构：

[1] Lodz Univ Technol, Inst Organ Chem, Zeromskiego 116, PL-90924 Lodz, Poland

[2] Lodz Univ Technol, Inst Gen & Ecol Chem, Zeromskiego 116, PL-90924 Lodz, Poland

来源：

TETRAHEDRON LETTERS | 2019年 / 60卷 / 07期

关键词：

Michael addition; HWE olefination; 1,1,3,3-Tetramethylguanidine; Cyclohexane-1,3-diones; Coumarins; Tetrahydroxanthenones; ONE-POT; FUNCTIONALIZED; 4H-CHROMENES; PHLOROGLUCINOL;

D O I：

10.1016/j.tetlet.2019.01.022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A strategically new approach to 9-substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones is described. The protocol includes TMG promoted, conjugate addition of cyclohexane-1,3-diones to 3-(diethoxyphosphoryl)coumarins and a domino transesterification-cyclodehydration reaction of the adducts obtained. Modification of the tetrahydroxanthenone at position 9 is reported for the first time. (C) 2019 Elsevier Ltd. All rights reserved.

引用

页码：538 / 540

页数：3

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