A facile synthesis of novel 9-substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones

被引：3
|
作者：
Deredas, Dariusz [1 ]
Lagiewka, Bartosz [1 ]
Maniukiewicz, Waldemar [2 ]
机构：
[1] Lodz Univ Technol, Inst Organ Chem, Zeromskiego 116, PL-90924 Lodz, Poland
[2] Lodz Univ Technol, Inst Gen & Ecol Chem, Zeromskiego 116, PL-90924 Lodz, Poland
来源：
TETRAHEDRON LETTERS | 2019年 / 60卷 / 07期
关键词：
Michael addition; HWE olefination; 1,1,3,3-Tetramethylguanidine; Cyclohexane-1,3-diones; Coumarins; Tetrahydroxanthenones; ONE-POT; FUNCTIONALIZED; 4H-CHROMENES; PHLOROGLUCINOL;
D O I：
10.1016/j.tetlet.2019.01.022
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A strategically new approach to 9-substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones is described. The protocol includes TMG promoted, conjugate addition of cyclohexane-1,3-diones to 3-(diethoxyphosphoryl)coumarins and a domino transesterification-cyclodehydration reaction of the adducts obtained. Modification of the tetrahydroxanthenone at position 9 is reported for the first time. (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页码：538 / 540
页数：3
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