Why have sustained increases in obesity and type 2 diabetes not offset declines in cardiovascular mortality over recent decades in Western countries?

被引：13
作者：
Capewell, Simon [1 ]
Buchan, Iain [2 ]
机构：
[1] Univ Liverpool, Dept Publ Hlth & Policy, Liverpool L69 3BX, Merseyside, England
[2] Univ Manchester, Sch Community Based Med, Manchester M13 9PL, Lancs, England
来源：
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES | 2012年 / 22卷 / 04期
基金：
英国医学研究理事会;
关键词：
Obesity; Type; 2; diabetes; Cardiovascular; Mortality; Trends; Western countries; BODY-MASS INDEX; DISEASE; ADULTS; HEALTH; TRENDS; RISK;
D O I：
10.1016/j.numecd.2012.01.005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The majority of Western countries have reported large falls in cardiovascular diseases (CVD) mortality rates since the 1970s. Yet since the 1980s, they have also experienced two-fold or three-fold increases in the prevalence of obesity and type 2 diabetes - both considered substantial risk factors for CVD. So why have these increasing risks apparently not impacted on CVD mortality falls? This viewpoint outlines the main factors involved; examines recent trends and apparent contradictions; offers some explanations for the trends; discusses how more usefully complex epidemiological models might lead to clearer evidence; offers some explanations for the trends; and explores the implications for CVD prevention. (c) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：307 / 311
页数：5
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