Four-component, five-centered, one-pot synthesis of 1-(1H-tetrazol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole derivatives

被引：12

作者：

Reddy, B. V. Subba ^{[1
]}

Kota, Kavya ^{[1
,3
]}

Rao, B. Maheshwar ^{[1
]}

Sridhar, B. ^{[2
]}

Mukkanti, K. ^{[3
]}

机构：

[1] CSIR, Indian Inst Chem Technol, Ctr Semiochem, Hyderabad, Andhra Pradesh, India

[2] CSIR, Indian Inst Chem Technol, Lab Xray Crystallog, Hyderabad, Andhra Pradesh, India

[3] JNTU, Dept Chem, Hyderabad 500085, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2016年 / 57卷 / 41期

关键词：

Multi-component reaction; Haloamine cyclization; Ugi-azide coupling; Tetrahydrocarbolines; Tetrazoles; MULTICOMPONENT REACTIONS; 3-COMPONENT REACTION; TETRAZOLE; ISOCYANIDES; CHEMISTRY; SURROGATE; BIOLOGY; IMINES; AMIDE;

D O I：

10.1016/j.tetlet.2016.08.067

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient four component, five centered coupling strategy has been developed for the synthesis of a novel series of 1-tetrazolyl-tetrahydro-beta-carboline derivatives in good yields. This method is effective for the synthesis of tetrazolyl tetrahydro-beta-carbolines in a one-pot operation. This method is operationally simple and works under mild conditions with diverse substrates. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：4529 / 4532

页数：4

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