G-CSF accelerates tissue regeneration in wound healing under diabetic conditions

被引：0
|
作者：
Mayer, B [1 ]
Rösken, F
Lepper, A
Wanner, GA
Menger, MD
机构：
[1] Univ Saarlandes, Inst Klin Expt Chirurg, D-66421 Homburg, Germany
[2] Rhein Westfal TH Aachen, Klin Plast Chirurg Hand & Verbrennungschirurg, Aachen, Germany
[3] Univ Spital Zurich, Unfallchirurg Klin, Zurich, Switzerland
来源：
LANGENBECKS ARCHIVES OF SURGERY | 1999年
关键词：
D O I：
暂无
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The effect of G-CSF on wound healing in diabetic mice was studied in the wound healing model of the ear of hairless mice. Daily application of G-CSF (i. p.; 120 mu g/kg) significantly accelerated both epithelialisation and neovascularisation, indicating improved wound healing, probably by a modulation of the local immune response and induction of fibroblast and endothelial cell proliferation and migration.
引用
收藏
页码：319 / 321
页数：3
相关论文
共 50 条
  • [31] Immunonutrition: Role in Wound Healing and Tissue Regeneration
    Chow, Oliver
    Barbul, Adrian
    ADVANCES IN WOUND CARE, 2014, 3 (01) : 46 - 53
  • [32] Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing
    I Hsu
    L G Parkinson
    Y Shen
    A Toro
    T Brown
    H Zhao
    R C Bleackley
    D J Granville
    Cell Death & Disease, 2014, 5 : e1458 - e1458
  • [33] Systemic Administration of G-CSF Accelerates Bone Regeneration and Modulates Mobilization of Progenitor Cells in a Rat Model of Distraction Osteogenesis
    Roseren, Flavy
    Pithioux, Martine
    Robert, Stephane
    Balasse, Laure
    Guillet, Benjamin
    Lamy, Edouard
    Roffino, Sandrine
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (07)
  • [34] Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing
    Hsu, I.
    Parkinson, L. G.
    Shen, Y.
    Toro, A.
    Brown, T.
    Zhao, H.
    Bleackley, R. C.
    Granville, D. J.
    CELL DEATH & DISEASE, 2014, 5 : e1458 - e1458
  • [35] Far-Infrared Therapy Accelerates Diabetic Wound Healing via Recruitment of Tissue Angiogenesis in a Full-Thickness Wound Healing Model in Rats
    Chen, Rong-Fu
    Liu, Keng-Fan
    Lee, Su-Shin
    Huang, Shu-Hung
    Wu, Yi-Chia
    Lin, Yun-Nan
    Wang, Chun-Ting
    Kuo, Yur-Ren
    BIOMEDICINES, 2021, 9 (12)
  • [36] Supernatant from activated omentum accelerates wound healing in diabetic mice wound model
    Li, Yu
    Hashikawa, Kazunobu
    Ebisawa, Katsumi
    Kambe, Miki
    Higuchi, Shinichi
    Kamei, Yuzuru
    NAGOYA JOURNAL OF MEDICAL SCIENCE, 2023, 85 (03): : 528 - 541
  • [37] Impact of tibial transverse transport in tissue regeneration and wound healing with perspective on diabetic foot ulcers
    Mukherjee, Sulagna
    Im, Seung-Soon
    WORLD JOURNAL OF DIABETES, 2024, 15 (05)
  • [38] An extract of the root of Lithospermun erythrorhison accelerates wound healing in diabetic mice
    Fujita, N
    Sakaguchi, I
    Kobayashi, H
    Ikeda, N
    Kato, Y
    Minamino, M
    Ishii, M
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2003, 26 (03) : 329 - 335
  • [39] Phosphorylated chitosan accelerates dermal wound healing in diabetic wistar rats
    Anushree, U.
    Punj, Pratik
    Vasumathi
    Bharati, Sanjay
    GLYCOCONJUGATE JOURNAL, 2023, 40 (01) : 19 - 31
  • [40] Neutralization of miR-615 Accelerates Angiogenesis and Diabetic Wound Healing
    Icli, Basak
    Ozdemir, Denizhan
    Liu, Xin
    Giatsidis, Giorgio
    Croce, Kevin
    Orgill, Dennis
    Feinberg, Mark
    DIABETES, 2017, 66 : A172 - A173
12345