G-CSF accelerates tissue regeneration in wound healing under diabetic conditions

被引：0
|
作者：
Mayer, B [1 ]
Rösken, F
Lepper, A
Wanner, GA
Menger, MD
机构：
[1] Univ Saarlandes, Inst Klin Expt Chirurg, D-66421 Homburg, Germany
[2] Rhein Westfal TH Aachen, Klin Plast Chirurg Hand & Verbrennungschirurg, Aachen, Germany
[3] Univ Spital Zurich, Unfallchirurg Klin, Zurich, Switzerland
来源：
LANGENBECKS ARCHIVES OF SURGERY | 1999年
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D O I：
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中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The effect of G-CSF on wound healing in diabetic mice was studied in the wound healing model of the ear of hairless mice. Daily application of G-CSF (i. p.; 120 mu g/kg) significantly accelerated both epithelialisation and neovascularisation, indicating improved wound healing, probably by a modulation of the local immune response and induction of fibroblast and endothelial cell proliferation and migration.
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页码：319 / 321
页数：3
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