Photoinduced Transition-Metal-Free Cross-Coupling of Aryl Halides with H-Phosphonates

被引：92

作者：

Zeng, Huiying ^{[1
]}

Dou, Qian ^{[1
]}

Li, Chao-Jun ^{[1
,2
,3
]}

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, 222 Tianshui Rd, Lanzhou 730000, Gansu, Peoples R China

[2] McGill Univ, Dept Chem, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada

[3] McGill Univ, FQRNT Ctr Green Chem & Catalysis, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada

来源：

ORGANIC LETTERS | 2019年 / 21卷 / 05期

关键词：

CATALYST-FREE; ROOM-TEMPERATURE; DIRECT ARYLATION; P-ARYLATION; BUTOXIDE; TRIFLUOROMETHYLATION; DIPHENYLPHOSPHINE; BONDS; OXIDE;

D O I：

10.1021/acs.orglett.8b04081

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Photoinduced transition-metal- and photosensitizer-free cross coupling of aryl halides (including Ar-Cl, Ar-Br, and Ar-I) with H-phosphonates (including dialkyl phosphonates and diarylphosphine oxides) is reported. Various functional groups were tolerated, including ester, methoxy, dimethoxy, alkyl, phenyl, trifluoromethyl, and heterocyclic compounds. This simple and green strategy provides a practical pathway to synthesize arylphosphine oxides.

引用

页码：1301 / 1305

页数：5

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