Eosinophils in patients suffering from atopic dermatitis and the relation to the occurrence of food allergy and other atopic diseases

被引:7
作者
Celakovska, J. [1 ,2 ]
Bukac, J. [3 ]
机构
[1] Charles Univ Prague, Dept Dermatol & Venerol, Fac Hosp, Hradec Kralove, Czech Republic
[2] Charles Univ Prague, Fac Med, Hradec Kralove, Czech Republic
[3] Charles Univ Prague, Fac Med, Dept Med Biophys, Hradec Kralove, Czech Republic
关键词
Atopic dermatitis; eosinophils; food allergy; food sensitization; asthma bronchiale; allergic rhinitis; total IgE; severity of atopic dermatitis; BLOOD EOSINOPHILIA; SERUM INTERLEUKIN-16; TISSUE EOSINOPHILIA; CATIONIC PROTEIN; IGE; HETEROGENEITY; FEATURES; INFANCY; CELLS;
D O I
10.1080/09540105.2016.1148669
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The aim of our study is to evaluate the count of eosinophils in peripheral blood in atopic dermatitis (AD) patients older than 14 years of age and to compare it with the occurrence of some other atopic diseases and parameters. One hundred and seventy-two patients were included in the study. According to our results, in AD patients with asthma bronchiale, rhinitis, food allergy, positive family history about atopy, with permanent skin lesions, with total IgE above 200 IU/ml, with the onset of AD under 5 years of age and in patients suffering from moderate or severe form of AD, the count of eosinophils is higher than the normal level of eosinophils. The normal count of eosinophils is recorded in patients suffering from mild form of AD and in patients suffering from food sensitization.
引用
收藏
页码:700 / 710
页数:11
相关论文
共 40 条
[1]  
Akan A, 2014, TURKISH J PEDIATR, V56, P121
[2]   T cells and T cell-derived cytokines as pathogenic factors in the nonallergic form of atopic dermatitis [J].
Akdis, CA ;
Akdis, M ;
Simon, D ;
Dibbert, B ;
Weber, M ;
Gratzl, S ;
Kreyden, O ;
Disch, R ;
Wüthrich, B ;
Blaser, K ;
Simon, HU .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1999, 113 (04) :628-634
[3]   What targeting eosinophils has taught us about their role in diseases [J].
Bochner, Bruce S. ;
Gleich, Gerald J. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (01) :16-25
[4]   Peripheral blood eosinophils and IL-4 in infancy in relation to the appearance of allergic disease during the first 6 years of life [J].
Borres, MP ;
Björkstén, B .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2004, 15 (03) :216-220
[5]   The millennium criteria for the diagnosis of atopic dermatitis [J].
Bos, JD ;
Van Leent, EJM ;
Smitt, JHS .
EXPERIMENTAL DERMATOLOGY, 1998, 7 (04) :132-138
[6]   A review of treatment with mepolizumab, an anti-IL-5 mAb, in hypereosinophilic syndromes and asthma [J].
Busse, William W. ;
Ring, Johannes ;
Huss-Marp, Johannes ;
Kahn, Jean-Emmanuel .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 125 (04) :803-813
[7]   Evaluation of food allergy to wheat, cow milk, egg, soy and peanuts in patients suffering from atopic dermatitis [J].
Celakovska, J. ;
Ettlerova, K. ;
Ettler, K. ;
Vaneckova, J. ;
Bukac, J. .
FOOD AND AGRICULTURAL IMMUNOLOGY, 2015, 26 (01) :26-37
[8]  
Celakovska Jarmila, 2013, Indian J Dermatol, V58, P247, DOI 10.4103/0019-5154.110893
[9]  
DENBURG JA, 1985, BLOOD, V66, P312
[10]  
Dhar Sandipan, 2005, Indian J Dermatol Venereol Leprol, V71, P246