A Strategy for Genomic Research on Common Cardiovascular Diseases Aiming at the Realization of Precision Medicine Personal Insights and Perspectives

被引：1

作者：

Morita, Hiroyuki ^{[1
]}

Komuro, Issei ^{[1
]}

机构：

[1] Univ Tokyo, Dept Cardiovasc Med, Tokyo, Japan

来源：

CIRCULATION RESEARCH | 2016年 / 119卷 / 08期

关键词：

cardiovascular diseases; cholesterol; genomics; lipids; precision medicine; VARIANTS; SUSCEPTIBILITY;

D O I：

10.1161/CIRCRESAHA.116.309802

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite the development of genomic research on common cardiovascular diseases, genetic variants and/or loci shown to be disease associated have been seldom applied to risk prediction in a clinical setting, although they could provide us with novel mechanistic insights into the pathophysiology and potential therapeutic targets. Here, we discuss the significance and limitations of the up-todate genomic studies on common diseases and propose what kind of genomic research should be prioritized in view of the realization of precision medicine.

引用

页码：900 / 903

页数：4

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