Prevalence of Gestational Diabetes in Triplet Pregnancies: A Retrospective Cohort Study and Meta-Analysis

被引：6

作者：

Hager, Marlene ^{[1
]}

Ott, Johannes ^{[1
]}

Castillo, Deirdre Maria ^{[1
]}

Springer, Stephanie ^{[2
]}

Seemann, Rudolf ^{[3
]}

Pils, Sophie ^{[4
,5
]}

机构：

[1] Med Univ Vienna, Dept Obstet & Gynecol, Clin Div Gynecol Endocrinol & Reprod Med, Spitalgasse 23, A-1090 Vienna, Austria

[2] Med Univ Vienna, Dept Obstet & Gynecol, Clin Div Obstet & Fetomaternal Med, Spitalgasse 23, A-1090 Vienna, Austria

[3] Med Univ Vienna, Dept Oral & Maxillofacial Surg, Spitalgasse 23, A-1090 Vienna, Austria

[4] Med Univ Vienna, Gynecol Canc Unit, Comprehens Canc Ctr, Clin Div Gen Gynecol & Gynecol Oncol, A-1090 Vienna, Austria

[5] Med Univ Vienna, Dept Obstet & Gynecol, Spitalgasse 23, A-1090 Vienna, Austria

来源：

JOURNAL OF CLINICAL MEDICINE | 2020年 / 9卷 / 05期

关键词：

triplets; multiple gestation; gestational diabetes; oral glucose tolerance test; pregnancy outcome; IN-VITRO FERTILIZATION; MATERNAL MORBIDITY; PERINATAL OUTCOMES; LONGITUDINAL CHANGES; GLUCOSE-TOLERANCE; NEONATAL OUTCOMES; REDUCTION; TWIN; QUADRUPLET; DELIVERY;

D O I：

10.3390/jcm9051523

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Over the last decades, there has been a substantial increase in the incidence of higher-order multiple gestations. Twin pregnancies are associated with an increased risk of gestational diabetes mellitus (GDM). The literature on GDM rates in triplet pregnancies is scarce. Methods: A retrospective cohort study was performed to assess the prevalence of GDM in women with a triplet pregnancy. GDM was defined through an abnormal oral glucose tolerance test (OGTT). A meta-analysis of GDM prevalence was also carried out. Results: A cohort of 60 women was included in the analysis. Of these, 19 (31.7%) were diagnosed with GDM. There were no differences in pregnancy outcomes between women with and without GDM. In the meta-analysis of 12 studies, which used a sound GDM definition, an estimated pooled prevalence of 12.4% (95% confidence interval: 6.9-19.1%) was found. In a leave-one-out sensitivity analysis, the estimated GDM prevalence ranged from 10.7% to 14.1%. Conclusion: The rate of GDM seems increased in women with triplets compared to singleton pregnancies. However, GDM did not impact short-term pregnancy outcomes.

引用

页数：13

共 67 条

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