The Neural Correlates of Negative Symptoms in Schizophrenia: Examples From MRI Literature

被引：8
作者：
Morch-Johnsen, Lynn [1 ,2 ,3 ]
Agartz, Ingrid [1 ,2 ,3 ,4 ]
Jensen, Jimmy [5 ]
机构：
[1] Diakonhjemmet Hosp, Dept Psychiat Res, Oslo, Norway
[2] Univ Oslo, NORMENT, Oslo, Norway
[3] Univ Oslo, KG Jebsen Ctr Psychosis Res, Inst Clin Med, Oslo, Norway
[4] Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, Stockholm, Sweden
[5] Kristianstad Univ, Ctr Psychol, Elmetorpsvagen 15, S-29188 Kristianstad, Sweden
来源：
CLINICAL EEG AND NEUROSCIENCE | 2018年 / 49卷 / 01期
关键词：
schizophrenia; negative symptoms; MRI; neuroimaging; avolition; WHITE-MATTER ABNORMALITIES; DEFICIT SCHIZOPHRENIA; NONDEFICIT SCHIZOPHRENIA; PSYCHOSIS PATIENTS; NAIVE PATIENTS; BRAIN-INJURY; VOLUME; APATHY; ACTIVATION; ASSOCIATIONS;
D O I：
10.1177/1550059417746214
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Negative symptoms of schizophrenia have a negative impact on psychosocial functioning and disease outcome. It is therefore important to investigate the pathophysiology underlying negative symptoms as this may aid the development of better treatment. In the current article, examples from studies investigating neural correlates of negative symptoms in schizophrenia are given. Investigations using both structural and functional magnetic resonance imaging are presented at different levels of symptomatology descriptions, from the more heterogenous construct of negative symptoms to more single discrete symptoms. Some methods to improve imaging studies of negative symptoms in schizophrenia are also suggested.
引用
收藏
页码：12 / 17
页数：6
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