Comparative analysis of the heme iron electronic structure and stereochemistry in tetrameric rabbit hemoglobin and monomeric soybean leghemoglobin a using Mossbauer spectroscopy with a high velocity resolution

被引：4

作者：

Alenkina, I. V. ^{[1
]}

Kumar, A. ^{[2
,3
]}

Berkovsky, A. L. ^{[4
]}

Oshtrakh, M. I. ^{[1
]}

机构：

[1] Ural Fed Univ, Inst Phys & Technol, Dept Expt Phys, Ekaterinburg 620002, Russia

[2] SUNY Buffalo, Jacobs Sch Med & Med Sci, Dept Biochem, Buffalo, NY 14214 USA

[3] Univ Delhi South Campus, Dept Biochem, New Delhi, India

[4] Minist Hlth & Social Dev Russian Federat, Hematol Res Ctr, Moscow 125167, Russia

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2018年 / 191卷

关键词：

Monomeric soybean leghemoglobin a; Tetrameric rabbit hemoglobin; Mossbauer spectroscopy; Iron electronic structure; Heme pocket structure; CALCULATED ELECTROMAGNETIC PROPERTIES; BIOMEDICAL-RESEARCH; CONTAINING PROTEINS; HUMAN OXYHEMOGLOBIN; CONTAINING BIOMOLECULES; HUMAN DEOXYHEMOGLOBIN; CHEMICAL-ANALYSIS; MODEL COMPOUNDS; OXYGEN; MYOGLOBIN;

D O I：

10.1016/j.saa.2017.10.055

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

A comparative study of tetrameric rabbit hemoglobin and monomeric soybean leghemoglobin a in the oxy- and deoxy-forms was carried out using Fe-57 Mossbauer spectroscopy with a high velocity resolution in order to analyze the heme iron electronic structure and stereochemistry in relation to the Mossbauer hyperfine parameters. The Mossbauer spectra of tetrameric rabbit hemoglobin in both forms were fitted using two quadrupole doublets related to the Fe-57 in alpha- and beta-subunits. In contrast, the Mossbauer spectra of monomeric soybean leghemoglobin a were fitted using: (i) two quadrupole doublets for the oxy-form related to two conformational states of the distal His E7 imidazole ring and different hydrogen bonding of oxygen molecule in the oxy-form and (ii) using three quadrupole doublets for deoxy-form related to three conformational states of the proximal His F8 imidazole ring. Small variations of Mossbauer hyperfine parameters related to small differences in the heme iron electronic structure and stereochemistry in tetrameric rabbit hemoglobin and monomeric soybean leghemoglobin alpha are discussed. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：547 / 557

页数：11

共 56 条

[1] GROUND AND LOW-LYING ELECTRONIC STATES OF OXYHEMOGLOBIN FROM TEMPERATURE-DEPENDENT MOSSBAUER AND SUSCEPTIBILITY DATA [J].

BACCI, M ;

CERDONIO, M ;

VITALE, S .

BIOPHYSICAL CHEMISTRY, 1979, 10 (01) :113-117

[2]

Dickson D.P.E., 1984, MOSSBAUER SPECTROSCO, V1, P339

[3] THEORETICAL DETERMINATION OF ELECTRONIC-STRUCTURE AND SPATIAL ARRANGEMENT OF FERROUS IRON IN DEOXYGENATED SPERM WHALE MYOGLOBIN AND HUMAN HEMOGLOBIN FROM MOSSBAUER EXPERIMENTS [J].

EICHER, H ;

BADE, D ;

PARAK, F .

JOURNAL OF CHEMICAL PHYSICS, 1976, 64 (04) :1446-1455

[4] THE CRYSTAL-STRUCTURE OF HUMAN DEOXYHEMOGLOBIN AT 1.74A RESOLUTION [J].

FERMI, G ;

PERUTZ, MF ;

SHAANAN, B ;

FOURME, R .

JOURNAL OF MOLECULAR BIOLOGY, 1984, 175 (02) :159-174

[5] Distinct reaction pathways followed upon reduction of oxy-heme oxygenase and oxy-myoglobin as characterized by Mossbauer spectroscopy [J].

Garcia-Serres, Ricardo ;

Davydov, Roman M. ;

Matsui, Toshitaka ;

Ikeda-Saito, Masao ;

Hoffman, Brian M. ;

Huynh, Boi Hanh .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (05) :1402-1412

[6]

HERMAN ZS, 1980, J AM CHEM SOC, V102, P1815, DOI 10.1021/ja00526a010

[7]

Huynh BH, 1983, STUD PHYS THEOR CHEM, V25, P490

[8]

Kamnev A.A., 2013, Mossbauer Spectroscopy: Applications in Chemistry, Biology, and Nanotechnology, P272

[9] COMPARATIVE QUANTUM-CHEMICAL ANALYSIS OF THE ELECTRONIC-STRUCTURE AND MOSSBAUER PARAMETERS OF THE ACTIVE-SITE MODELS FOR DEOXYMYOGLOBIN AND ALPHA-SUBUNIT AND BETA-SUBUNIT OF TETRAMERIC DEOXYHEMOGLOBIN [J].

KHLESKOV, VI ;

BURYKIN, BN ;

SMIRNOV, AB ;

OSHTRAKH, MI .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 155 (03) :1255-1260

[10] SEMIEMPIRICAL CALCULATIONS OF MODEL OXYHEME - VARIATION OF CALCULATED ELECTROMAGNETIC PROPERTIES WITH ELECTRONIC CONFIGURATION AND OXYGEN GEOMETRY [J].

KIRCHNER, RF ;

LOEW, GH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (14) :4639-4647

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