Verifying and Validating Quantitative Systems Pharmacology and In Silico Models in Drug Development: Current Needs, Gaps, and Challenges

被引：20

作者：

Musuamba, Flora T. ^{[1
,2
,3
]}

Bursi, Roberta ^{[4
]}

Manolis, Efthymios ^{[1
,5
]}

Karlsson, Kristin ^{[1
,6
]}

Kulesza, Alexander ^{[7
]}

Courcelles, Eulalie ^{[7
]}

Boissel, Jean-Pierre ^{[7
]}

Lesage, Raphaelle ^{[8
]}

Crozatier, Cecile ^{[9
]}

Voisin, Emmanuelle M. ^{[9
]}

Rousseau, Cecile F. ^{[9
]}

Marchal, Thierry ^{[10
]}

Alessandrello, Rossana ^{[11
]}

Geris, Liesbet ^{[8
,12
]}

机构：

[1] EMA Modelling & Simulat Working Party, Amsterdam, Netherlands

[2] Fed Agcy Med & Hlth Prod, Brussels, Belgium

[3] Univ Lubumbashi, Fac Sci Pharmaceut, Lubumbashi, DEM REP CONGO

[4] InSilicoTrials Technol, Milan, Italy

[5] European Med Agcy, Amsterdam, Netherlands

[6] Med Prod Agcy, Uppsala, Sweden

[7] Novadiscovery, Lyon, France

[8] Katholieke Univ Leuven, Leuven, Belgium

[9] Voisin Consulting Life Sci, Paris, France

[10] Ansys, Wavre, Belgium

[11] AQuAS Agcy Hlth Qual & Assessment Catalonia, Catalonia, Spain

[12] Univ Liege, Liege, Belgium

来源：

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY | 2020年 / 9卷 / 04期

关键词：

D O I：

10.1002/psp4.12504

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：195 / 197

页数：3

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