STRN-ALK Fusion in Lung Adenocarcinoma with Brain Metastasis Responded Well to Ensartinib: A Case Report

被引：5
|
作者：
Zhang, Linlin [1 ]
Xiao, Ping [1 ]
Meng, Fanlu [1 ]
Zhong, Diansheng [1 ]
机构：
[1] Tianjin Med Univ, Gen Hosp, Dept Med Oncol, Tianjin 300052, Peoples R China
来源：
CURRENT ONCOLOGY | 2022年 / 29卷 / 10期
基金：
中国国家自然科学基金;
关键词：
STRN-ALK fusion; lung adenocarcinoma; brain metastasis; ensartinib;
D O I：
10.3390/curroncol29100530
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
STRN-ALK fusion is a rare ALK rearrangement identified in non-small cell lung cancer (NSCLC) patients. Here, we reported a case of lung adenocarcinomas with brain metastasis, harboring STRN-ALK fusion, responded well to ensartinib. This case report could provide more information for the therapeutic strategy selecting of NSCLC patients harboring STRN-ALK fusion.
引用
收藏
页码：6749 / 6753
页数：5
相关论文
共 50 条
  • [31] LMO7-ALK Fusion in a Lung Adenocarcinoma Patient With Crizotinib: A Case Report
    Yang, Yanlong
    Zheng, Hongbo
    Li, Zizhe
    Shi, Shuchen
    Zhong, Lang
    Gong, Longlong
    Lan, Bin
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [32] A non-functional 5′ ALK fusion validated at the RNA level as a classical EML4-ALK that responds well to the novel ALK inhibitor ensartinib: A case report
    Yang, Hong
    Li, Haojing
    Fang, Yu
    Li, Zhijun
    Zhu, Jianhua
    Liu, Huan
    Lu, Chao
    Zhang, Xiaoyan
    Ma, Tonghui
    Zhang, Cuiying
    FRONTIERS IN MEDICINE, 2022, 9
  • [33] Non-small cell lung cancer patient with a rare UGP2-ALK fusion protein responded well to alectinib: a case report
    Chen, Liulin
    Chu, Daifang
    Li, Wangping
    Zhang, Haitao
    ANTI-CANCER DRUGS, 2024, 35 (01) : 97 - 100
  • [34] An ALK-positive lung adenocarcinoma with gastric and skin metastasis: a case report and literature review
    Duan, Xueqin
    Zhao, Xinhan
    Wang, Shuhong
    ANNALS OF PALLIATIVE MEDICINE, 2021, 10 (05) : 5797 - 5807
  • [35] First case report of ensartinib in a patient with metastatic ALK rearranged lung cancer with ALK I1171N mutation: a case report
    Shuang Yang
    Weineng Feng
    Yanming Deng
    Jianmiao Liang
    World Journal of Surgical Oncology, 21
  • [36] First case report of ensartinib in a patient with metastatic ALK rearranged lung cancer with ALK I1171N mutation: a case report
    Yang, Shuang
    Feng, Weineng
    Deng, Yanming
    Liang, Jianmiao
    WORLD JOURNAL OF SURGICAL ONCOLOGY, 2023, 21 (01)
  • [37] Coexistence of a Novel NBAS-ALK, EML4-ALK Double-Fusion in a Lung Adenocarcinoma Patient With LM and Response to Ensartinib
    Xu, X.
    Li, N.
    Fan, Y.
    JOURNAL OF THORACIC ONCOLOGY, 2022, 17 (09) : S445 - S445
  • [38] A Novel LINC00478/LINC01549 Intergenic Region-ALK Fusion Responded Well to Alectinib in a Patient With Lung Adenocarcinoma
    Peng, Wei
    Li, Si
    Li, Lijian
    Xiao, Mingzhe
    Zhong, Jincai
    JTO CLINICAL AND RESEARCH REPORTS, 2021, 2 (01):
  • [39] Lung adenocarcinoma with an uncommon CCDC85A-ALK fusion responding to alectinib: A case report
    Lin, Jieheng
    Wang, Wenping
    Lin, Jietao
    Chen, Ruilian
    Cao, Yang
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2022, 26 (20) : 5326 - 5329
  • [40] Novel MRPS9-ALK Fusion Mutation in a Lung Adenocarcinoma Patient: A Case Report
    Zhou, Huamiao
    Xu, Binyue
    Xu, Jili
    Zhu, Guomeng
    Guo, Yong
    FRONTIERS IN ONCOLOGY, 2021, 11
12345