JAK/STAT-dependent gene regulation by cytokines

被引：93
作者：
Hebenstreit, D [1 ]
Horejs-Hoeck, J [1 ]
Duschl, A [1 ]
机构：
[1] Salzburg Univ, Dept Biol Mol, A-5020 Salzburg, Austria
来源：
DRUG NEWS & PERSPECTIVES | 2005年 / 18卷 / 04期
关键词：
D O I：
10.1358/dnp.2005.18.4.908658
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The Janus kinase-signal transducer and activator of transcription (Jak-STAT) pathway is essential for the signal transduction of many cytokines. Dysregulation of Jak-STAT signaling is associated with various human diseases. Recent studies have helped to shed some light on regulatory mechanisms that modify quantity and quality of the signaling response. Here, we summarize our current knowledge on Jak-STAT signaling. (c) 2005 Prous Science. All rights reserved.
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收藏
页码：243 / 249
页数：7
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