A randomized, placebo-controlled, double-blinded, crossover trial of pioglitazone for severe asthma

被引:22
作者
Kaler, Maryann [1 ]
Barochia, Amisha V. [1 ]
Weir, Nargues A. [1 ,4 ]
Cuento, Rosemarie A. [1 ]
Stylianou, Mario [2 ]
Roth, Mark J. [3 ]
Filie, Armando C. [3 ]
Vaughey, Ellen C. [5 ]
Nathan, Steven D. [4 ]
Levine, Stewart J. [1 ]
机构
[1] NHLBI, Lab Asthma & Lung Inflammat, Cardiovasc & Pulm Branch, NIH, Bldg 10, Bethesda, MD 20892 USA
[2] NHLBI, Off Biostat Res, NIH, Bldg 10, Bethesda, MD 20892 USA
[3] NCI, Pathol Lab, Ctr Canc Res, NIH, Bldg 10, Bethesda, MD 20892 USA
[4] Inova Fairfax Hosp, Adv Lung Dis & Lung Transplant Clin, Falls Church, VA USA
[5] Northern Virginia Pulm & Crit Care Associates, Annandale, VA USA
基金
美国国家卫生研究院;
关键词
GAMMA AGONIST ROSIGLITAZONE;
D O I
10.1016/j.jaci.2017.05.033
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:1716 / 1718
页数:4
相关论文
共 9 条
  • [1] Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial
    Anderson, J. R.
    Mortimer, K.
    Pang, L.
    Smith, K. M.
    Bailey, H.
    Hodgson, D. B.
    Shaw, D. E.
    Knox, A. J.
    Harrison, T. W.
    [J]. PLOS ONE, 2016, 11 (08):
  • [2] Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation
    Belvisi, MG
    Hele, DJ
    Birrell, MA
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2006, 533 (1-3) : 101 - 109
  • [3] A pilot randomized controlled trial of pioglitazone for the treatment of poorly controlled asthma in obesity
    Dixon, Anne E.
    Subramanian, Meenakumari
    DeSarno, Michael
    Black, Kendall
    Lane, Lisa
    Holguin, Fernando
    [J]. RESPIRATORY RESEARCH, 2015, 16
  • [4] Treatment with a peroxisomal proliferator activated receptor gamma agonist has a modest effect in the allergen challenge model in asthma: A randomised controlled trial
    Richards, Duncan B.
    Bareille, Philippe
    Lindo, Emma L.
    Quinn, Dean
    Farrow, Stuart N.
    [J]. RESPIRATORY MEDICINE, 2010, 104 (05) : 668 - 674
  • [5] Thiazolidinediones and the risk of asthma exacerbation among patients with diabetes: a cohort study
    Rinne, Seppo T.
    Feemster, Laura C.
    Collins, Bridget F.
    Au, David H.
    Perkins, Mark
    Bryson, Christopher L.
    O'Riordan, Thomas G.
    Liu, Chuan-Fen
    [J]. ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, 2014, 10
  • [6] The use of the peroxisome proliferator-activated receptors γ agonist rosiglitazone to treat airway hyperreactivity
    Sandhu, Manbir Singh
    Dimov, Vesselin
    Sandhu, Arveen Kaur
    Walters, Ryan W.
    Wichman, Tammy
    Casale, Thomas
    [J]. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2012, 109 (01) : 75 - 77
  • [7] Bronchodilatory Effect of the PPAR-γ Agonist Rosiglitazone in Smokers With Asthma
    Spears, M.
    Donnelly, I.
    Jolly, L.
    Brannigan, M.
    Ito, K.
    McSharry, C.
    Lafferty, J.
    Chaudhuri, R.
    Braganza, G.
    Bareille, P.
    Sweeney, L.
    Adcock, I. M.
    Barnes, P. J.
    Wood, S.
    Thomson, N. C.
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2009, 86 (01) : 49 - 53
  • [8] Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms
    Straus, Daniel S.
    Glass, Christopher K.
    [J]. TRENDS IN IMMUNOLOGY, 2007, 28 (12) : 551 - 558
  • [9] Peroxisome Proliferator Activated Receptor Ligands as Regulators of Airway Inflammation and Remodelling in Chronic Lung Disease
    Ward, Jane Elizabeth
    Tan, Xiahui
    [J]. PPAR RESEARCH, 2007, 2007