Amphotericin B-deoxycholate overdose due to administration error in pediatric patients

被引:4
作者
Groeneveld, Susanne [1 ]
Verweij, Paul E. [4 ,5 ]
Van't Hek, Louis [2 ]
Bokkerink, Jos P. M. [3 ]
Warris, Adilia [1 ,5 ]
机构
[1] Radboud Univ Nijmegen Med Ctr, Dept Pediat, NL-6500 HB Nijmegen, Netherlands
[2] Radboud Univ Nijmegen Med Ctr, Dept Pediat Intens Care, NL-6500 HB Nijmegen, Netherlands
[3] Radboud Univ Nijmegen Med Ctr, Dept Pediat Oncol, NL-6500 HB Nijmegen, Netherlands
[4] Radboud Univ Nijmegen Med Ctr, Dept Med Microbiol, NL-6500 HB Nijmegen, Netherlands
[5] Radboud Univ Nijmegen Med Ctr, Nijmegen Univ Ctr Infect Dis, NL-6500 HB Nijmegen, Netherlands
关键词
amphotericin B; overdose; children; hyperkalemia;
D O I
10.1080/13693780701658280
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Due to the similarity of their generic names, the use of amphotericin B-deoxycholate and liposomal amphotericin B could cause confusion in daily practice. We report two cases of amphotericin B-deoxycholate overdose in infants due to administration errors which raises the issue that the use of this antifungal agent should be questioned because of its severe side effects.
引用
收藏
页码:185 / 187
页数:3
相关论文
共 6 条
  • [1] Barcia JP, 1998, PHARMACOTHERAPY, V18, P874
  • [2] AMPHOTERICIN-B OVERDOSE IN PEDIATRIC-PATIENTS WITH ASSOCIATED CARDIAC-ARREST
    CLEARY, JD
    HAYMAN, J
    SHERWOOD, J
    LASALA, GP
    PIAZZAHEPP, T
    [J]. ANNALS OF PHARMACOTHERAPY, 1993, 27 (06) : 715 - 719
  • [3] What is the current and future status of conventional amphotericin B?
    Kleinberg, Michael
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2006, 27 : S12 - S16
  • [4] Fatal amphotericin B overdose due to administration of nonlipid formulation instead of lipid formulation
    Mohr, JF
    Hall, AC
    Ericsson, CD
    Ostrosky-Zeichner, L
    [J]. PHARMACOTHERAPY, 2005, 25 (03): : 426 - 428
  • [5] Oude Lashof A M L, 2004, Ned Tijdschr Geneeskd, V148, P1665
  • [6] FATAL OVERDOSE OF AMPHOTERICIN-B IN 2 PRETERM INFANTS
    PERLMAN, JM
    ACARREGUI, M
    GARD, JW
    [J]. DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS, 1991, 17 (3-4): : 187 - 190