Genetic toxicology of abused drugs: a brief review

被引：39
作者：
Li, JH
Lin, LF
机构：
[1] Dept Hlth Execut Yuan Cabinet, Natl Narcot Bureau, Taipei, Taiwan
[2] Natl Yang Ming Univ, Inst Genet, Taipei 112, Taiwan
来源：
MUTAGENESIS | 1998年 / 13卷 / 06期
关键词：
D O I：
10.1093/mutage/13.6.557
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Although numerous studies have been conducted on abused drugs, most focus on the problems of addiction (dependence) and their neurotoxicities. Now accumulated data have demonstrated that the genotoxicity and/or carcinogenicity of abused drugs can also be detrimental to our health. In this review, commonly abused substances, including LSD, opiates (diacetylmorphine, morphine, opium and codeine), cocaine, cannabis, betel quid and khat, are discussed for their potential genotoxicity/carcinogenicity. The available literature in the held, although not as abundant as for neurotoxicity, clearly indicates the capability of abused drugs to induce genotoxicity.
引用
收藏
页码：557 / 565
页数：9
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