A new procedure for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes supernatant

被引：5
作者：
Mascini, EM [1 ]
Hazenberg, MAJ [1 ]
Verhage, LAE [1 ]
Holm, SE [1 ]
Verhoef, J [1 ]
vanDijk, H [1 ]
机构：
[1] UMEA UNIV,DEPT CLIN BACTERIOL,UMEA,SWEDEN
来源：
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 1996年 / 3卷 / 06期
关键词：
D O I：
10.1128/CDLI.3.6.779-781.1996
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
An important role in the pathogenesis of invasive group A streptococcal disease has been ascribed to the production of streptococcal pyrogenic exotoxin A. We present a new technique for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes NY-5 supernate, which is highly efficient with respect to yield (35%), purity (greater than or equal to 99%), and time.
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页码：779 / 781
页数：3
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