Dynamics of icosahedral viruses: What does viral tiling theory teach us?

被引：5

作者：

Peeters, Kasper ^{[2
]}

Taormina, Anne ^{[1
]}

机构：

[1] Univ Durham, Dept Math Sci, Durham, England

[2] Univ Utrecht, Inst Theoret Phys, NL-3508 TA Utrecht, Netherlands

来源：

COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE | 2008年 / 9卷 / 3-4期

基金：

英国工程与自然科学研究理事会; 英国科学技术设施理事会;

关键词：

icosahedral virus; viral tiling theory; RYMV; bacteriophage;

D O I：

10.1080/17486700802168270

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We present a top-down approach to the study of the dynamics of icosahedral virus capsids, in which each protein is approximated by a point mass. Although this represents a rather crude coarse-graining, we argue that it highlights several generic features of vibrational spectra which have been overlooked so far. We furthermore discuss the consequences of approximate inversion symmetry as well as the role played by viral tiling theory in the study of virus capsid vibrations.

引用

页码：211 / 220

页数：10

共 30 条

[1] HARMONIC DYNAMICS OF PROTEINS - NORMAL-MODES AND FLUCTUATIONS IN BOVINE PANCREATIC TRYPSIN-INHIBITOR [J].

BROOKS, B ;

KARPLUS, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (21) :6571-6575

[2] Large conformational changes in the maturation of a simple RNA virus, Nudaurelia capensis ω virus (NωV) [J].

Canady, MA ;

Tihova, M ;

Hanzlik, TN ;

Johnson, JE ;

Yeager, M .

JOURNAL OF MOLECULAR BIOLOGY, 2000, 299 (03) :573-584

[3] PHYSICAL PRINCIPLES IN CONSTRUCTION OF REGULAR VIRUSES [J].

CASPAR, DLD ;

KLUG, A .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1962, 27 :1-&

[4] LOW-FREQUENCY COLLECTIVE MOTION IN BIOMACROMOLECULES AND ITS BIOLOGICAL FUNCTIONS [J].

CHOU, KC .

BIOPHYSICAL CHEMISTRY, 1988, 30 (01) :3-48

[5] Virus maturation involving large subunit rotations and local refolding [J].

Conway, JF ;

Wikoff, WR ;

Cheng, N ;

Duda, RL ;

Hendrix, RW ;

Johnson, JE ;

Steven, AC .

SCIENCE, 2001, 292 (5517) :744-748

[6]

Cornwell J. F., 1984, Group Theory in Physics, V1

[7] Dynamical implications of Viral Tiling Theory [J].

ElSawy, K. M. ;

Taormina, A. ;

Twarock, R. ;

Vaughan, L. .

JOURNAL OF THEORETICAL BIOLOGY, 2008, 252 (02) :357-369

[8] Molecular dynamics simulations of the complete satellite tobacco mosaic virus [J].

Freddolino, PL ;

Arkhipov, AS ;

Larson, SB ;

McPherson, A ;

Schulten, K .

STRUCTURE, 2006, 14 (03) :437-449

[9] DYNAMICS OF A SMALL GLOBULAR PROTEIN IN TERMS OF LOW-FREQUENCY VIBRATIONAL-MODES [J].

GO, N ;

NOGUTI, T ;

NISHIKAWA, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (12) :3696-3700

[10] Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy [J].

Heymann, JB ;

Cheng, NQ ;

Newcomb, WW ;

Trus, BL ;

Brown, JC ;

Steven, AC .

NATURE STRUCTURAL BIOLOGY, 2003, 10 (05) :334-341

← 1 2 3 →