Interaction of Silver Nanoparticles with Plasma Proteins

被引：2
|
作者：
Kaur, Harmandeep [1 ]
Tripathi, S. K. [1 ]
机构：
[1] Panjab Univ, Dept Phys, Chandigarh 160014, India
来源：
INTERNATIONAL CONFERENCE ON ADVANCES IN CONDENSED AND NANO MATERIALS (ICACNM-2011) | 2011年 / 1393卷
关键词：
Nanoparticles; Plasma proteins; TEM;
D O I：
10.1063/1.3653650
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Bio-functionalization or surface modification is an important technique to obtain biocompatibility in metal nanoparticles for biomedical applications. In this study, colloidal silver nanoparticles have been prepared by chemical reduction method and characterized by TEM & UV-Vis spectroscopy. We have studied binding of plasma proteins with colloidal silver nanoparticles. Particle characterization, effect on particle size and surface charge has been investigated by dynamic light scattering (DLS) and transmission electron microscopy (TEM). DLS measurements revealed that average particle hydrodynamic diameter (z-average) increased after incubation of silver nanoparticles with plasma. TEM Images after binding of plasma proteins to the Ag nanoparticles showed protein coating over these nanoparticles
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页数：2
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