BIOT 180-Using cationic polyelectrolytes to precipitate host cell impurities in monoclonal antibody purification

被引:0
|
作者
Peram, Thanmaya [1 ]
McDonald, Paul [1 ]
Fahrner, Robert [1 ]
机构
[1] Genentech Inc, Early Stage Purificat, PR&D, San Francisco, CA 94080 USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 238卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
180-BIOT
引用
收藏
页数:1
相关论文
共 37 条
  • [1] Monoclonal Antibody Purification Using Cationic Polyelectrolytes: An Alternative to Column Chromatography
    Peram, Thanmaya
    McDonald, Paul
    Carter-Franklin, Jayme
    Fahrner, Robert
    BIOTECHNOLOGY PROGRESS, 2010, 26 (05) : 1322 - 1331
  • [2] Host cell protein impurities in chromatographic polishing steps for monoclonal antibody purification
    Levy, Nicholas E.
    Valente, Kristin N.
    Lee, Kelvin H.
    Lenhoff, Abraham M.
    BIOTECHNOLOGY AND BIOENGINEERING, 2016, 113 (06) : 1260 - 1272
  • [3] Buffer system improves the removal of host cell protein impurities in monoclonal antibody purification
    Lakatos, Daniel
    Idler, Martina
    Stibitzky, Selina
    Amann, Jennifer
    Schuschkewitz, Jakob
    Krayl, Dominik
    Liebau, Judith
    Grosch, Jan-Hendrik
    Arango Gutierrez, Erik
    Kluters, Simon
    BIOTECHNOLOGY AND BIOENGINEERING, 2024, 121 (12) : 3869 - 3880
  • [4] Selective Antibody Precipitation Using Polyelectrolytes: A Novel Approach to the Purification of Monoclonal Antibodies
    McDonald, Paul
    Victa, Corazon
    Carter-Franklin, Jayme N.
    Fahrner, Robert
    BIOTECHNOLOGY AND BIOENGINEERING, 2009, 102 (04) : 1141 - 1151
  • [5] Chromatographic properties of host cell protein impurities in downstream purification of monoclonal antibodies
    Levy, Nicholas E.
    Valente, Kristin N.
    Lee, Kelvin H.
    Lenhoff, Abraham M.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [6] BIOT 287-Reduction of host cell DNA using charged filters at Protein A capture for monoclonal antibody production
    Wesner, John M.
    Lepore, Joseph A.
    Gill, Doreen L.
    Bink, Lee R.
    Peters, Stanley
    Drewicz, John
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 236
  • [7] BIOT 283-Monoclonal antibody purification using continuous countercurrent ion-exchange chromatography
    Mueller-Spaeth, Thomas
    Aumann, Lars
    Stroehlein, Guido
    Kornmann, Henri
    Morbidelli, Massimo
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 236
  • [8] Identification and Characterization of Host Cell Protein Product-Associated Impurities in Monoclonal Antibody Bioprocessing
    Levy, Nicholas E.
    Valente, Kristin N.
    Choe, Leila H.
    Lee, Kelvin H.
    Lenhoff, Abraham M.
    BIOTECHNOLOGY AND BIOENGINEERING, 2014, 111 (05) : 904 - 912
  • [9] Novel peptide ligands for antibody purification provide superior clearance of host cell protein impurities
    Reese, Hannah R.
    Xiao, Xingqing
    Shanahan, Calvin C.
    Van den Driessche, George A.
    Fourches, Denis
    Carbonell, Ruben G.
    Hall, Carol K.
    Menegatti, Stefano
    JOURNAL OF CHROMATOGRAPHY A, 2020, 1625
  • [10] Identification and characterization of host cell protein product-associated impurities in monoclonal antibody downstream processing
    Levy, Nicholas E.
    Valente, Kristin
    Lee, Kelvin H.
    Lenhoff, Abraham M.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243