Class 1 integrons in multidrug-resistant non-typhoidal Salmonella enterica isolated in Spain between 2002 and 2004

被引：25

作者：

Rodriguez, Irene ^{[1
]}

Rodicio, M. Rosario ^{[1
]}

Herrera-Leon, Silvia ^{[2
]}

Echeita, Aurora ^{[2
]}

Mendoza, M. Carmen ^{[1
]}

机构：

[1] Univ Oviedo, Dept Biol Func, Area Microbiol, Fac Med, E-33006 Oviedo, Spain

[2] Inst Salud Carlos III, Lab Nacl Referencia Salmonella & Shigella, Madrid 28220, Spain

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2008年 / 32卷 / 02期

关键词：

Salmonella enterica; multidrug resistance; class; 1; integrons; integron mapping;

D O I：

10.1016/j.ijantimicag.2008.03.005

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In this study, 119 multidrug-resistant isolates of non-typhoidal Salmonella enterica serovars collected in Spain (2002-2004) were screened for integrons. Among the isolates, 73.1% contained class 1 integrons, however classes 2 and 3 were not detected. Integrons containing gene cassettes were found in S. Enteritidis (16/32), S. Typhimurium biphasic (18/32) and monophasic [4,5,12:i:-] (11/19), S. Virchow (17/18) and S. Brandenburg (8/8),but not in S. Hadar(0/10). Ten complete and four incomplete gene cassettes, combined in 10 variable regions, were identified, one of which (2100 bp/dfrA1-597 bp-aadA24) was a new description. Most integrons mapped on plasmids of ca. 40-340kb. Exceptions were 1000 bp/aadA2 and 1200 bp/bla(PSE-1) found on the chromosome of biphasic S. Typhimurium, probably as par. of SGI1-like structures. (C) 2008 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

引用

页码：158 / 164

页数：7

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