Phase separation in biology

被引：278
作者：
Alberti, Simon [1 ]
机构：
[1] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany
来源：
CURRENT BIOLOGY | 2017年 / 27卷 / 20期
关键词：
TRANSITIONS; STRESS;
D O I：
10.1016/j.cub.2017.08.069
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：R1097 / R1102
页数：7
相关论文
共 10 条
  • [1] Are aberrant phase transitions a driver of cellular aging?
    Alberti, Simon
    Hyman, Anthony A.
    [J]. BIOESSAYS, 2016, 38 (10) : 959 - 968
  • [2] Biomolecular condensates: organizers of cellular biochemistry
    Banani, Salman F.
    Lee, Hyun O.
    Hyman, Anthony A.
    Rosen, Michael K.
    [J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2017, 18 (05) : 285 - 298
  • [3] Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
    Brangwynne, Clifford P.
    Eckmann, Christian R.
    Courson, David S.
    Rybarska, Agata
    Hoege, Carsten
    Gharakhani, Joebin
    Juelicher, Frank
    Hyman, Anthony A.
    [J]. SCIENCE, 2009, 324 (5935) : 1729 - 1732
  • [4] Coexisting Liquid Phases Underlie Nucleolar Subcompartments
    Feric, Marina
    Vaidya, Nilesh
    Harmon, Tyler S.
    Mitrea, Diana M.
    Zhu, Lian
    Richardson, Tiffany M.
    Kriwacki, Richard W.
    Pappu, Rohit V.
    Brangwynne, Clifford P.
    [J]. CELL, 2016, 165 (07) : 1686 - 1697
  • [5] Liquid-Liquid Phase Separation in Biology
    Hyman, Anthony A.
    Weber, Christoph A.
    Juelicher, Frank
    [J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30, 2014, 30 : 39 - 58
  • [6] Phase transitions in the assembly of multivalent signalling proteins
    Li, Pilong
    Banjade, Sudeep
    Cheng, Hui-Chun
    Kim, Soyeon
    Chen, Baoyu
    Guo, Liang
    Llaguno, Marc
    Hollingsworth, Javoris V.
    King, David S.
    Banani, Salman F.
    Russo, Paul S.
    Jiang, Qiu-Xing
    Nixon, B. Tracy
    Rosen, Michael K.
    [J]. NATURE, 2012, 483 (7389) : 336 - U129
  • [7] A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
    Patel, Avinash
    Lee, Hyun O.
    Jawerth, Louise
    Maharana, Shovamayee
    Jahnel, Marcus
    Hein, Marco Y.
    Stoynov, Stoyno
    Mahamid, Julia
    Saha, Shambaditya
    Franzmann, Titus M.
    Pozniakovski, Andrej
    Poser, Ina
    Maghelli, Nicola
    Royer, Loic A.
    Weigert, Martin
    Myers, Eugene W.
    Grill, Stephan
    Drechsel, David
    Hyman, Anthony A.
    Alberti, Simon
    [J]. CELL, 2015, 162 (05) : 1066 - 1077
  • [8] Cell adaptation upon stress: the emerging role of membrane-less compartments
    Rabouille, Catherine
    Alberti, Simon
    [J]. CURRENT OPINION IN CELL BIOLOGY, 2017, 47 : 34 - 42
  • [9] Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response
    Riback, Joshua A.
    Katanski, Christopher D.
    Kear-Scott, Jamie L.
    Pilipenko, Evgeny V.
    Rojek, Alexandra E.
    Sosnick, Tobin R.
    Drummond, D. Allan
    [J]. CELL, 2017, 168 (06) : 1028 - +
  • [10] Phase separation of signaling molecules promotes T cell receptor signal transduction
    Su, Xiaolei
    Ditlev, Jonathon A.
    Hui, Enfu
    Xing, Wenmin
    Banjade, Sudeep
    Okrut, Julia
    King, David S.
    Taunton, Jack
    Rosen, Michael K.
    Vale, Ronald D.
    [J]. SCIENCE, 2016, 352 (6285) : 595 - 599
1