Extended-release methylphenidate monotherapy in patients with comorbid social anxiety disorder and adult attention-deficit/hyperactivity disorder: retrospective case series

被引：8

作者：

Koyuncu, Ahmet ^{[1
]}

Celebi, Fahri ^{[2
]}

Ertekin, Erhan ^{[3
]}

Kok, Burcu Ece ^{[2
]}

Tukel, Rasit ^{[3
]}

机构：

[1] Acad Social Phobia Ctr, Ataturk Mah Ikitelli Cad 126 A, Istanbul, Turkey

[2] Istanbul Univ, Istanbul Med Sch, Dept Child & Adolescent Psychiat, Istanbul, Turkey

[3] Istanbul Univ, Istanbul Med Sch, Dept Psychiat, Istanbul, Turkey

来源：

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY | 2017年 / 7卷 / 11期

关键词：

attention-deficit/hyperactivity disorder; comorbidity; extended-release methylphenidate; social anxiety disorder; treatment; DEFICIT HYPERACTIVITY DISORDER; AGE-DEPENDENT DECLINE; PSYCHIATRIC COMORBIDITY; ATOMOXETINE TREATMENT; CONTROLLED-TRIAL; ADHD; CHILDREN; PREVALENCE; PHOBIA; PREDICTORS;

D O I：

10.1177/2045125317714193

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Background: The relationship between social anxiety disorder (SAD) and attention-deficit/hyperactivity disorder (ADHD) is a subject which has recently become a topic of interest for research. Methods: In this study, 20 patients with comorbid SAD and adult ADHD who were treated with extended-release methylphenidate monotherapy were evaluated retrospectively. Results: Clinical response for both ADHD and SAD symptoms was observed in 17 of 20 patients. Overall, one patient did not respond to treatment and two patients dropped out of treatment at the beginning due to adverse effects. Conclusion: Extended-release methylphenidate improved both SAD and ADHD symptoms and was generally well tolerated. Further studies are required to investigate the relationship between SAD and ADHD.

引用

页码：241 / 247

页数：7

共 51 条

[1] ATOMOXETINE TREATMENT IN ADULTS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER AND COMORBID SOCIAL ANXIETY DISORDER [J].

Adler, Lenard A. ;

Liebowitz, Michael ;

Kronenberger, Williain ;

Qiao, Meihua ;

Rubin, Richard ;

Hollandbeck, Millie ;

Deldar, Ahmed ;

Schuh, Kory ;

Durell, Todd .

DEPRESSION AND ANXIETY, 2009, 26 (03) :212-221

[2] Age-dependent decline of symptoms of attention deficit hyperactivity disorder: Impact of remission definition and symptom type [J].

Biederman, J ;

Mick, E ;

Faraone, SV .

AMERICAN JOURNAL OF PSYCHIATRY, 2000, 157 (05) :816-818

[3]

BIEDERMAN J, 1993, AM J PSYCHIAT, V150, P1792

[4]

Biederman J, 1996, ARCH GEN PSYCHIAT, V53, P437

[5] Predictors of persistent ADHD: An 11-year follow-up study [J].

Biederman, Joseph ;

Petty, Carter R. ;

Clarke, Allison ;

Lomedico, Alexandra ;

Faraone, Stephen V. .

JOURNAL OF PSYCHIATRIC RESEARCH, 2011, 45 (02) :150-155

[6] How persistent is ADHD? A controlled 10-year follow-up study of boys with ADHD [J].

Biederman, Joseph ;

Petty, Carter R. ;

Evans, Maggie ;

Small, Jacqueline ;

Faraone, Stephen V. .

PSYCHIATRY RESEARCH, 2010, 177 (03) :299-304

[7] Comorbidity of generalized social anxiety disorder and depression in a pediatric primary care sample [J].

Chavira, DA ;

Stein, MB ;

Bailey, K ;

Stein, MT .

JOURNAL OF AFFECTIVE DISORDERS, 2004, 80 (2-3) :163-171

[8] Response to methylphenidate in children with ADHD and comorbid anxiety [J].

Diamond, IR ;

Tannock, R ;

Schachar, RJ .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1999, 38 (04) :402-409

[9]

Edel M-A, 2010, Eur J Med Res, V15, P403

[10] Epidemiology of ADHD in Chilean children and adolescents [J].

Eloisa de la Barra, Flora ;

Vicente, Benjamin ;

Saldivia, Sandra ;

Melipillan, Roberto .

ADHD-ATTENTION DEFICIT AND HYPERACTIVITY DISORDERS, 2013, 5 (01) :1-8

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