The neuronal cytoskeleton: An insight for neurosurgeons

被引：3
作者：
Fitzpatrick, MO
Dewar, D
Teasdale, GM
Graham, DI
机构：
[1] UNIV GLASGOW,HUGH FRASER NEUROSCI LABS,GLASGOW G61 1QH,LANARK,SCOTLAND
[2] SO GEN HOSP,INST NEUROL SCI,DEPT NEUROSURG,GLASGOW G51 4TF,LANARK,SCOTLAND
[3] SO GEN HOSP,INST NEUROL SCI,DEPT NEUROPATHOL,GLASGOW G51 4TF,LANARK,SCOTLAND
来源：
BRITISH JOURNAL OF NEUROSURGERY | 1996年 / 10卷 / 05期
关键词：
axonal injury; cerebral ischaemia; cytoskeleton; neuron; trauma;
D O I：
10.1080/02688699647122
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The cytoskeleton is important in the structure and function of the neuron. Disruption of the cytoskeletal proteins occurs in a variety of forms of acute brain injury including cerebral ischaemia and diffuse anonal injury. The final common pathway mediating neuronal cell death involves loss of the integrity of the cytoskeleton and these disturbances may have a key role in the progression of events following acute brain injury. This review aims to provide an insight into the neuronal cytoskeleton in the normal state and in disorders encountered in neurosurgical practice.
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收藏
页码：483 / 487
页数：5
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