Application areas of 3D bioprinting

被引：225

作者：

Ozbolat, Ibrahim T. ^{[1
,2
]}

Peng, Weijie ^{[1
,2
,3
]}

Ozbolat, Veli ^{[4
]}

机构：

[1] Penn State Univ, Engn Sci & Mech Dept, State Coll, PA 16802 USA

[2] Penn State Univ, Huck Inst Life Sci, State Coll, PA 16802 USA

[3] Nanchang Univ, Dept Pharmacol, Nanchang 330006, JX, Peoples R China

[4] Cukurova Univ, Ceyhan Engn Fac, Dept Mech Engn, TR-01330 Adana, Turkey

来源：

DRUG DISCOVERY TODAY | 2016年 / 21卷 / 08期

基金：

美国国家科学基金会;

关键词：

STEM-CELLS; VALVE CONDUITS; TISSUE; HYDROGEL; SKIN; CANCER; BIOFABRICATION; FABRICATION; CONSTRUCTS; SCAFFOLD;

D O I：

10.1016/j.drudis.2016.04.006

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Three dimensional (3D) bioprinting has been a powerful tool in patterning and precisely placing biologics, including living cells, nucleic acids, drug particles, proteins and growth factors, to recapitulate tissue anatomy, biology and physiology. Since the first time of cytoscribing cells demonstrated in 1986, bioprinting has made a substantial leap forward, particularly in the past 10 years, and it has been widely used in fabrication of living tissues for various application areas. The technology has been recently commercialized by several emerging businesses, and bioprinters and bioprinted tissues have gained significant interest in medicine and pharmaceutics. This Keynote review presents the bioprinting technology and covers a first-time comprehensive overview of its application areas from tissue engineering and regenerative medicine to pharmaceutics and cancer research.

引用

页码：1257 / 1271

页数：15

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