Flow Electrosynthesis of Sulfoxides, Sulfones, and Sulfoximines without Supporting Electrolytes

被引：39
作者：
Amri, Nasser [1 ]
Wirth, Thomas [1 ]
机构：
[1] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, Wales
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 22期
关键词：
EFFICIENT SYNTHESIS; SULFIDES; OXIDATION; CONSTRUCTION; CATALYST; ACCESS; SCAFFOLDS; THIOLS;
D O I：
10.1021/acs.joc.1c00860
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient electrochemical flow process for the selective oxidation of sulfides to sulfoxides and sulfones and of sulfoxides to N-cyanosulfoximines has been developed. In total, 69 examples of sulfoxides, sulfones, and N-cyanosulfoximines have been synthesized in good to excellent yields and with high current efficiencies. The synthesis was assisted and facilitated through a supporting electrolyte-free, fully automated electrochemical protocol that highlights the advantages of flow electrolysis.
引用
收藏
页码：15961 / 15972
页数：12
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