Radiation Treatment for Age-Related Macular Degeneration

被引：14

作者：

Silva, Ruwan A. ^{[2
]}

Moshfeghi, Andrew A. ^{[2
]}

Kaiser, Peter K. ^{[3
]}

Singh, Rishi P. ^{[3
]}

Moshfeghi, Darius M. ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Eye Inst Stanford, Dept Ophthalmol,Vitreoretinal Ctr, Palo Alto, CA 94303 USA

[2] Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USA

[3] Cleveland Clin Fdn, Cole Eye Inst, Cleveland, OH 44195 USA

来源：

SEMINARS IN OPHTHALMOLOGY | 2011年 / 26卷 / 03期

关键词：

Radiation; Age-Related Macular Degeneration; Retina; Choroidal Neovascular Membrane; Brachytherapy; SUBFOVEAL CHOROIDAL NEOVASCULARIZATION; EXTERNAL-BEAM IRRADIATION; GROWTH-FACTOR VEGF; PHOTODYNAMIC THERAPY; HISTOLOGICAL-FINDINGS; CONTROLLED TRIAL; RADIOTHERAPY; MEMBRANES; MACULOPATHY; BRACHYTHERAPY;

D O I：

10.3109/08820538.2011.554486

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Age-related macular degeneration (AMD) remains a devastating cause of visual loss among elderly individuals. While considerable progress has been made towards combating the disease, most recently with intravitreal anti-VEGF agents, visual outcomes are still limited by continued retinal pigment epithelium (RPE) degeneration and subsequent neurosensory retinal atrophy. Among the promising new treatment options being explored, radiotherapy appears apt to address the multifactorial etiology of AMD. Current investigative studies underway will hopefully yield clinical efficacy to complement this theoretical suitability for arresting visual loss.

引用

页码：121 / 130

页数：10

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