iSMART: An Integrated Cloud Computing Web Server for Traditional Chinese Medicine for Online Virtual Screening, de novo Evolution and Drug Design

被引：60
作者：
Chang, Kai-Wei [1 ]
Tsai, Tsung-Ying [1 ]
Chen, Kuan-Chung [1 ]
Yang, Shun-Chieh [1 ]
Huang, Hung-Jin [1 ]
Chang, Tung-Ti [1 ]
Sun, Mao-Feng [1 ,2 ]
Chen, Hsin-Yi [3 ]
Tsai, Fuu-Jen [2 ,3 ]
Chen, Calvin Yu-Chian [1 ,3 ,4 ,5 ]
机构：
[1] China Med Univ, Lab Computat & Syst Biol, Sch Chinese Med, Taichung 40402, Taiwan
[2] China Med Univ Hosp, Dept Acupuncture, Taichung, Taiwan
[3] Asia Univ, Dept Bioinformat, Taichung 41354, Taiwan
[4] Harvard Univ, Dept Syst Biol, Sch Med, Boston, MA 02115 USA
[5] MIT, Cambridge, MA 02139 USA
来源：
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 2011年 / 29卷 / 01期
关键词：
Traditional Chinese medicine (TCM); Cloud-computing; Docking; Screening; Systems biology; MOLECULAR DOCKING; V3; LOOP; INHIBITOR;
D O I：
10.1080/073911011010524988
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：243 / 250
页数：8
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  • [1] Computational Model of the HIV-1 Subtype A V3 Loop: Study on the Conformational Mobility for Structure-Based Anti-AIDS Drug Design
    Andrianov, Alexander M.
    Anishchenko, Ivan V.
    [J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2009, 27 (02) : 179 - 193
  • [2] Immunophilins and HIV-1 V3 Loop For Structure-Based Anti-AIDS Drug Design
    Andrianov, Alexander M.
    [J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2009, 26 (04) : 445 - 454
  • [3] Gene Ontology: tool for the unification of biology
    Ashburner, M
    Ball, CA
    Blake, JA
    Botstein, D
    Butler, H
    Cherry, JM
    Davis, AP
    Dolinski, K
    Dwight, SS
    Eppig, JT
    Harris, MA
    Hill, DP
    Issel-Tarver, L
    Kasarskis, A
    Lewis, S
    Matese, JC
    Richardson, JE
    Ringwald, M
    Rubin, GM
    Sherlock, G
    [J]. NATURE GENETICS, 2000, 25 (01) : 25 - 29
  • [4] Statistical models for text segmentation
    Beeferman, D
    Berger, A
    Lafferty, J
    [J]. MACHINE LEARNING, 1999, 34 (1-3) : 177 - 210
  • [5] Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety
    Burgin, Alex B.
    Magnusson, Olafur T.
    Singh, Jasbir
    Witte, Pam
    Staker, Bart L.
    Bjornsson, Jon M.
    Thorsteinsdottir, Margret
    Hrafnsdottir, Sigrun
    Hagen, Timothy
    Kiselyov, Alex S.
    Stewart, Lance J.
    Gurney, Mark E.
    [J]. NATURE BIOTECHNOLOGY, 2010, 28 (01) : 63 - U93
  • [6] Docking Simulation and Competitive Experiments Validate the Interaction Between the 2,5-Xylidine Inhibitor and Rigidoporus lignosus Laccase
    Cambria, Maria Teresa
    Di Marino, Daniele
    Falconi, Mattia
    Garavaglia, Silvia
    Cambria, Antonio
    [J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2010, 27 (04) : 501 - 509
  • [7] Key Features for Designing Phosphodiesterase-5 Inhibitors
    Chang, Tung-Ti
    Huang, Hung-Jin
    Lee, Kuei-Jen
    Yu, Hsin Wei
    Chen, Hsin-Yi
    Tsai, Fuu-Jen
    Sun, Mao-Feng
    Chen, Calvin Yu-Chian
    [J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2010, 28 (03) : 309 - 321
  • [8] TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico
    Chen, Calvin Yu-Chian
    [J]. PLOS ONE, 2011, 6 (01):
  • [9] Virtual Screening and Drug Design for PDE-5 Receptor from Traditional Chinese Medicine Database
    Chen, Calvin Yu-Chian
    [J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2010, 27 (05) : 627 - 640
  • [10] Ligand-Based Dual Target Drug Design for H1N1: Swine Flu- A Preliminary First Study
    Chen, Chien-Yu
    Chang, Yea-Huey
    Bau, Da-Tian
    Huang, Hung-Jin
    Tsai, Fuu-Jen
    Tsai, Chang-Hai
    Chen, Calvin Yu-Chian
    [J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2009, 27 (02) : 171 - 178
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