Hepatitis B Virus Reactivation Potentiated by Biologics

被引：23
作者：
Ogawa, Eiichi [1 ]
Wei, Mike T. [2 ]
Nguyen, Mindie H. [2 ]
机构：
[1] Kyushu Univ Hosp, Dept Gen Internal Med, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan
[2] Stanford Univ, Med Ctr, Dept Med, Div Gastroenterol & Hepatol, 750 Welch Rd,Suite 210, Palo Alto, CA 94304 USA
来源：
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2020年 / 34卷 / 02期
关键词：
Hepatitis B virus; Reactivation; Prophylaxis; Nucleos(t)ide analogue; CHEMOTHERAPY-INDUCED REACTIVATION; HBV REACTIVATION; C VIRUS; HEPATOCELLULAR-CARCINOMA; LAMIVUDINE THERAPY; ANTIVIRAL THERAPY; TARGETING BTK; T-CELLS; INFECTION; PATHOGENESIS;
D O I：
10.1016/j.idc.2020.02.009
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Hepatitis B virus (HBV) reactivation can be a serious complication for patients with chronic or resolved HBV infection when treated with biologics. For HBsAg-positive patients receiving biologics, the risk of HBV reactivation is moderate to high. HBsAg-negative/anti-HBc positive patients are at lower risk of HBV reactivation than HBsAg-positive patients. However, patients taking anti-CD20 agents, such as rituximab, have high risk of HBV reactivation (>10%), so antiviral prophylactic therapies are required. This review provides the different classes of biologics associated with HBV reactivation, stratifies the various reactivation risk levels by HBV status and biologic agent, and discusses management strategies.
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收藏
页码：341 / +
页数：20
相关论文
共 87 条
  • [1] Ahmed A, 1999, AM J GASTROENTEROL, V94, P249, DOI 10.1111/j.1572-0241.1999.00808.x
  • [2] Safety of long-term biologic therapy in rheumatologic patients with a previously resolved hepatitis B viral infection
    Barone, Michele
    Notarnicola, Antonella
    Lopalco, Giuseppe
    Viggiani, Maria Teresa
    Sebastiani, Francesco
    Covelli, Michele
    Iannone, Florenzo
    Avolio, Alfonso W.
    Di Leo, Alfredo
    Cantarini, Luca
    Lapadula, Giovanni
    [J]. HEPATOLOGY, 2015, 62 (01) : 40 - 46
  • [3] Hepatitis B Virus Infection Among American Patients with Chronic Hepatitis C Virus Infection: Prevalence, Racial/Ethnic Differences, and Viral Interactions
    Bini, Edmund J.
    Perumalswami, Ponni V.
    [J]. HEPATOLOGY, 2010, 51 (03) : 759 - 766
  • [4] Abatacept: A Review in Rheumatoid Arthritis
    Blair, Hannah A.
    Deeks, Emma D.
    [J]. DRUGS, 2017, 77 (11) : 1221 - 1233
  • [5] Structural organization of the hepatitis B virus minichromosome
    Bock, CT
    Schwinn, S
    Locarnini, S
    Fyfe, J
    Manns, MP
    Trautwein, C
    Zentgraf, H
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2001, 307 (01) : 183 - 196
  • [6] Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
    Byrd, John C.
    Furman, Richard R.
    Coutre, Steven E.
    Flinn, Ian W.
    Burger, Jan A.
    Blum, Kristie A.
    Grant, Barbara
    Sharman, Jeff P.
    Coleman, Morton
    Wierda, William G.
    Jones, Jeffrey A.
    Zhao, Weiqiang
    Heerema, Nyla A.
    Johnson, Amy J.
    Sukbuntherng, Juthamas
    Chang, Betty Y.
    Clow, Fong
    Hedrick, Eric
    Buggy, Joseph J.
    James, Danelle F.
    O'Brien, Susan
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (01) : 32 - 42
  • [7] Cainelli F, 2001, AM J GASTROENTEROL, V96, P1651
  • [8] HBV Reactivation in Patients Treated with Antitumor Necrosis Factor-Alpha (TNF-alpha)Agents for Rheumatic and Dermatologic Conditions: A Systematic Review and Meta-Analysis
    Cantini, Fabrizio
    Boccia, Stefania
    Goletti, Delia
    Iannone, Florenzo
    Leoncini, Emanuele
    Panic, Nikola
    Prignano, Francesca
    Gaeta, Giovanni Battista
    [J]. INTERNATIONAL JOURNAL OF RHEUMATOLOGY, 2014, 2014
  • [9] In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab
    Caratelli, Sara
    Arriga, Roberto
    Sconocchia, Tommaso
    Ottaviani, Alessio
    Lanzilli, Giulia
    Pastore, Donatella
    Cenciarelli, Carlo
    Venditti, Adriano
    Del Principe, Maria Ilaria
    Lauro, Davide
    Landoni, Elisa
    Du, Hongwei
    Savoldo, Barbara
    Ferrone, Soldano
    Dotti, Gianpietro
    Sconocchia, Giuseppe
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2020, 146 (01) : 236 - 247
  • [10] Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis
    Chamian, Francesca
    Lin, Shao-Lee
    Lee, Edmund
    Kikuchi, Toyoko
    Gilleaudeau, Patricia
    Sullivan-Whalen, Mary
    Cardinale, Irma
    Khatcherian, Artemis
    Novitskaya, Inna
    Wittkowski, Knut M.
    Krueger, James G.
    Lowes, Michelle A.
    [J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2007, 5 (1)
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