Identification of TRD-35 as Potent and Selective DRAK2 Inhibitor

被引：10
作者：
Ali, Imran [1 ,2 ]
Park, Sangjun [1 ,2 ]
Jung, Myoung Eun [1 ]
Lee, Nari [1 ,2 ]
Bibi, Maimoona [1 ,2 ]
Chae, Chong Hak [1 ]
Yang, Kyung-Min [3 ]
Kim, Seong-Jin [3 ]
Choi, Gildon [1 ,2 ]
Lee, Kwangho [1 ,2 ]
机构：
[1] Korea Res Inst Chem Technol, Therapeut & Biotechnol Div, Daejeon 34114, South Korea
[2] Univ Sci & Technol, Med Chem & Pharmacol, Daejeon 34113, South Korea
[3] Seoul Natl Univ, Precis Med Res Ctr, Adv Inst Convergence Technol, Suwon 16229, South Korea
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2020年 / 41卷 / 05期
关键词：
DRAK2; DRAK1; DAPK1; DAPK3; Kinase; Inhibitor; 3-Aminopyrazoylpyrimidine; PROTEIN-KINASE; DISCOVERY; DERIVATIVES; FAMILY;
D O I：
10.1002/bkcs.12005
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Proposed binding mode of TRD-35 (thick cyan sticks) in the DRAK2.
引用
收藏
页码：567 / 569
页数：3
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