There are several response properties that distinguish cortical simple cells of cat Vf. layer 4 from the geniculate cells that provide their input. We have recently demonstrated that a developmentally motivated pattern of intracortical inhibition, in conjunction with the observed pattern of geniculocortical connections, can robustly account for the contrast-invariance of simple cell orientation tuning. We now show that this same model circuit unexpectedly accounts for the low-pass shift in the temporal frequency tuning curves of cortical cells relative to geniculate cells. This arises when NMDA-mediated excitatory conductances are included in the thalamocortical synapses, at levels observed experimentally. (C) 2001 Published by Elsevier Science B.V.
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Ecole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, FranceEcole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, France
Angulo, MC
Rossier, J
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Ecole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, FranceEcole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, France
Rossier, J
Audinat, E
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Ecole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, FranceEcole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, France
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UNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USAUNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USA
CRAIR, MC
MALENKA, RC
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UNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USAUNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USA
机构:
Ecole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, FranceEcole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, France
Angulo, MC
Rossier, J
论文数: 0引用数: 0
h-index: 0
机构:
Ecole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, FranceEcole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, France
Rossier, J
Audinat, E
论文数: 0引用数: 0
h-index: 0
机构:
Ecole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, FranceEcole Super Phys & Chim Ind Ville Paris, CNRS UMR 7637, F-75231 Paris 5, France
机构:
UNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USAUNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USA
CRAIR, MC
MALENKA, RC
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USAUNIV CALIF SAN FRANCISCO, CTR NEUROBIOL & PSYCHIAT, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USA